2021
Clinical Impact of Cardiovascular Magnetic Resonance in Cancer Patients With Suspected Cardiomyopathy
Heidari-Bateni G, Durand J, Iliescu C, Gladish G, Deswal A, Patel A, Kim P, Song J, Hassan S, Palaskas N, Baldassarre L, Bucciarelli-Ducci C, Lopez-Mattei J. Clinical Impact of Cardiovascular Magnetic Resonance in Cancer Patients With Suspected Cardiomyopathy. Frontiers In Cardiovascular Medicine 2021, 8: 734820. PMID: 34765654, PMCID: PMC8576269, DOI: 10.3389/fcvm.2021.734820.Peer-Reviewed Original ResearchLeft ventricular ejection fractionCardiovascular magnetic resonanceHigher left ventricular ejection fractionTertiary cancer centerCancer patientsClinical impactInfiltrative cardiomyopathyMultiple myelomaCancer CenterPresumptive diagnosisClinical diagnosisCardio-oncology practiceCancer diagnosisVentricular ejection fractionSignificant clinical impactClinical decision makingLogistic regression modelsBaseline characteristicsConsecutive patientsEjection fractionEndomyocardial biopsyDiverse etiologiesCMR resultsMagnetic resonancePatients57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity
Cuomo J, Ragheb E, Feher A, Kwan J, Huber S, Mojibian H, Peters D, Sinusas A, Baldassarre L. 57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity. Journal Of Clinical And Translational Science 2021, 5: 141-142. PMCID: PMC8827987, DOI: 10.1017/cts.2021.761.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsVentricular ejection fractionLV strainCardiotoxicity groupCheckpoint inhibitorsEjection fractionProspective studyCardiac functionNormal left ventricular ejection fractionLeft ventricular ejection fractionCardiac magnetic resonance imagingCardiac magnetic resonance imaging techniquesGlobal longitudinal LV strainAbnormal troponin valuesEvidence of cardiotoxicityProportion of myocardiumLarge prospective studiesLongitudinal LV strainStudy of patientsSteady-state free precession cine imagesAbnormal cardiac functionCircumferential LV strainT2-weighted imagingMagnetic resonance imagingDysfunctional segmentsLeft ventricular myocardial strain and tissue characterization by cardiac magnetic resonance imaging in immune checkpoint inhibitor associated cardiotoxicity
Higgins AY, Arbune A, Soufer A, Ragheb E, Kwan JM, Lamy J, Henry M, Cuomo JR, Charifa A, Gallegos C, Hull S, Coviello JS, Bader AS, Peters DC, Huber S, Mojibian HR, Sinusas AJ, Kluger H, Baldassarre LA. Left ventricular myocardial strain and tissue characterization by cardiac magnetic resonance imaging in immune checkpoint inhibitor associated cardiotoxicity. PLOS ONE 2021, 16: e0246764. PMID: 33606757, PMCID: PMC7895343, DOI: 10.1371/journal.pone.0246764.Peer-Reviewed Original ResearchConceptsGlobal longitudinal strainImmune checkpoint inhibitorsLate gadolinium enhancementRecovery of LVEFLake Louise criteriaCheckpoint inhibitorsNormal LVEFAverage global longitudinal strainPresence of LGEAbnormal global longitudinal strainCardiac magnetic resonance imagingCorrect clinical contextEvaluation of myocarditisLeft ventricular dysfunctionVentricular ejection fractionDiagnosis of myocarditisLeft ventricular strainCardiac magnetic resonanceLeft ventricular myocardial strainOvert left ventricular dysfunctionVentricular myocardial strainMagnetic resonance imagingAtrial strainVentricular dysfunctionVentricular strain
2019
CARDIAC MAGNETIC RESONANCE IMAGING FEATURE TRACKING STRAIN AS A SENSITIVE MARKER OF CARDIOTOXICITY IN BREAST CANCER PATIENTS COMPARED WITH LEFT VENTRICULAR EJECTION FRACTION
Kwan J, Arbune A, Henry M, Dupee D, Soufer A, Baldassarre L. CARDIAC MAGNETIC RESONANCE IMAGING FEATURE TRACKING STRAIN AS A SENSITIVE MARKER OF CARDIOTOXICITY IN BREAST CANCER PATIENTS COMPARED WITH LEFT VENTRICULAR EJECTION FRACTION. Journal Of The American College Of Cardiology 2019, 73: 1666. DOI: 10.1016/s0735-1097(19)32272-7.Peer-Reviewed Original ResearchMyocarditis with checkpoint inhibitor immunotherapy: case report of late gadolinium enhancement on cardiac magnetic resonance with pathology correlate
Gallegos C, Rottmann D, Nguyen VQ, Baldassarre LA. Myocarditis with checkpoint inhibitor immunotherapy: case report of late gadolinium enhancement on cardiac magnetic resonance with pathology correlate. European Heart Journal - Case Reports 2019, 3: yty149. PMID: 31020225, PMCID: PMC6439394, DOI: 10.1093/ehjcr/yty149.Peer-Reviewed Case Reports and Technical NotesLate gadolinium enhancementCardiovascular magnetic resonanceCardiac complicationsGadolinium enhancementAnti-programmed cell death protein 1 monoclonal antibodyCell death protein 1 monoclonal antibodyLeft ventricular ejection fractionNon-ischemic patternAcute heart failureCheckpoint inhibitor therapyRefractory cardiogenic shockCarotid artery dissectionCheckpoint inhibitor immunotherapyVentricular ejection fractionArea of myocardiumCardiac magnetic resonanceDirect histological correlationAreas of LGEArtery dissectionCardiogenic shockCheckpoint inhibitorsImmunosuppressive therapyVentricular dysfunctionEjection fractionHeart failure