2021
Reward drinking and naltrexone treatment response among young adult heavy drinkers
Roos CR, Bold KW, Witkiewitz K, Leeman RF, DeMartini KS, Fucito LM, Corbin WR, Mann K, Kranzler HR, O'Malley SS. Reward drinking and naltrexone treatment response among young adult heavy drinkers. Addiction 2021, 116: 2360-2371. PMID: 33620746, PMCID: PMC8328878, DOI: 10.1111/add.15453.Peer-Reviewed Original Research
2018
Drinking Goals and Attainment in a Naltrexone Trial of Young Adult Heavy Drinkers
DeMartini KS, Foster DW, Corbin WR, Fucito LM, Romano D, Leeman RF, Kranzler HR, O’Malley S. Drinking Goals and Attainment in a Naltrexone Trial of Young Adult Heavy Drinkers. Journal Of Consulting And Clinical Psychology 2018, 86: 765-774. PMID: 30138015, PMCID: PMC6435339, DOI: 10.1037/ccp0000323.Peer-Reviewed Original ResearchConceptsTreatment outcomesAdult heavy drinkersYoung adult heavy drinkersHeavy drinkersDrinking goalEnd of treatmentPeak drinkingBetter treatment outcomesAlcohol use disorderImpact treatment outcomesTypical drinkingYoung adult drinkersEfficacy trialsUse disordersBrief counselingGoal settingIntervention effectsGoal-setting exercisesAdult drinkersDrinkersOutcomesDrinkingTreatmentImportant targetMidtreatment
2016
Exploring the Utility of Web-Based Social Media Advertising to Recruit Adult Heavy-Drinking Smokers for Treatment
Bold KW, Hanrahan TH, O'Malley SS, Fucito LM. Exploring the Utility of Web-Based Social Media Advertising to Recruit Adult Heavy-Drinking Smokers for Treatment. Journal Of Medical Internet Research 2016, 18: e107. PMID: 27194456, PMCID: PMC4889869, DOI: 10.2196/jmir.5360.Peer-Reviewed Original ResearchConceptsHeavy drinking smokersWeb-based surveyScreening eligibilityAdult smokersAlcohol useCurrent treatment goalsMajority of smokersGreater New HavenHeavy alcohol consumptionSerious medical problemNon-heavy drinkersPerson followDaily smokingTreatment goalsSmokersSmoking behaviorAlcohol consumptionHealth outcomesHeavy drinkersScreening surveyMedical problemsTreatment studiesSmokingInitial eligibilityCertain subgroupsLongitudinal Findings From a Randomized Clinical Trial of Naltrexone for Young Adult Heavy Drinkers
DeMartini KS, Gueorguieva R, Leeman RF, Corbin WR, Fucito LM, Kranzler HR, O’Malley S. Longitudinal Findings From a Randomized Clinical Trial of Naltrexone for Young Adult Heavy Drinkers. Journal Of Consulting And Clinical Psychology 2016, 84: 185-190. PMID: 26654213, PMCID: PMC4941818, DOI: 10.1037/ccp0000053.Peer-Reviewed Original ResearchConceptsPercent days abstinentFirst placebo-controlled trialPercent days heavy drinkingHeavy drinkingPlacebo-controlled trialLong-term outcomesHeavy drinking daysYoung adults ages 18Adults ages 18Naltrexone conditionActive medicationPlacebo groupPharmacotherapy trialsAdult heavy drinkersYoung adult heavy drinkersNonsignificant decreaseSignificant benefitsYear posttreatmentDays abstinentDrinking daysMost outcomesSingle interventionHeavy drinkersTreatment improvementAge 18
2013
Predictors of Interest in an Alcohol Reduction Clinical Trial of Naltrexone among Undergraduates
Leeman RF, Corbin WR, Fucito LM, Urwin JW, O’Malley S. Predictors of Interest in an Alcohol Reduction Clinical Trial of Naltrexone among Undergraduates. Journal Of Addiction Research & Therapy 2013, 4: 151. PMID: 24511431, PMCID: PMC3917969, DOI: 10.4172/2155-6105.1000151.Peer-Reviewed Original ResearchClinical trialsPredictors of interestTrend-level predictorCurrent cigarette smokingNon-white raceCigarette smokingDrinking reductionsPast-year drinkersTreatment engagementHeavy drinkersReduction messagesAlcohol-related negative consequencesYoung adultsSignificant predictorsTrialsNaltrexonePredictorsRandom sampleDrinkersRegression modelsFull regression modelCounselingEquivalent levelsHigher numberMedicationsEarly Subjective Response and Acquired Tolerance as Predictors of Alcohol Use and Related Problems in a Clinical Sample
Corbin WR, Scott C, Leeman RF, Fucito LM, Toll BA, O'Malley SS. Early Subjective Response and Acquired Tolerance as Predictors of Alcohol Use and Related Problems in a Clinical Sample. Alcohol Clinical And Experimental Research 2013, 37: 490-497. PMID: 23347236, PMCID: PMC3586307, DOI: 10.1111/j.1530-0277.2012.01956.x.Peer-Reviewed Original ResearchConceptsEarly subjective responseLow subjective responseAlcohol use disorderAlcohol-related problemsRisk factorsSubjective responsesAlcohol useYoung adultsBrief motivational counselingClinical samplesInitial subjective responseDrinking behaviorHeavy drinking young adultsSignificant alcohol problemsClinical trialsProtective effectModerate drinkersUse disordersMotivational counselingPrior studiesCurrent studyHeavy drinkersHazardous drinkingAlcohol effectsWeekly drinking
2011
Co-occurring marijuana use is associated with medication nonadherence and nonplanning impulsivity in young adult heavy drinkers
Peters EN, Leeman RF, Fucito LM, Toll BA, Corbin WR, O'Malley SS. Co-occurring marijuana use is associated with medication nonadherence and nonplanning impulsivity in young adult heavy drinkers. Addictive Behaviors 2011, 37: 420-426. PMID: 22189052, PMCID: PMC3288288, DOI: 10.1016/j.addbeh.2011.11.036.Peer-Reviewed Original ResearchConceptsCo-occurring marijuana useAdult heavy drinkersYoung adult heavy drinkersHeavy drinkersMedication nonadherenceAlcohol consumptionHigh-risk clinical profileMarijuana useAlcohol-related negative consequencesUse of cigarettesAlcohol-induced disinhibitionBrief individual counselingClinical profileClinical trialsSelf-report assessmentsNonadherenceHeavy drinkingYoung adultsDemographic characteristicsDrinkersIndividual counselingClinical samplesHeavy alcoholMedicationsDrinkingA preliminary investigation of varenicline for heavy drinking smokers
Fucito LM, Toll BA, Wu R, Romano DM, Tek E, O’Malley S. A preliminary investigation of varenicline for heavy drinking smokers. Psychopharmacology 2011, 215: 655-663. PMID: 21221531, PMCID: PMC3645986, DOI: 10.1007/s00213-010-2160-9.Peer-Reviewed Original ResearchConceptsHeavy drinking smokersActive medicationPretreatment groupAlcohol cravingHeavy drinkersOpen-label phaseSmoking cessation pharmacotherapyEffects of vareniclineHeavy drinking daysGreater reductionPlacebo leadVarenicline pretreatmentCessation counselingCessation pharmacotherapyAbstinence ratesCigarette smokingVareniclineSmoking changesDrinking daysPotential treatmentSmokingAlcohol dependenceEntire study periodSmokersHeavy drinking