2013
Chapter 13 Principles of Cell Signaling
Cantley L. Chapter 13 Principles of Cell Signaling. 2013, 369-403. DOI: 10.1016/b978-0-12-381462-3.00013-6.Peer-Reviewed Original ResearchComplex multicellular organismsAppropriate cellular responsesCell-cell junctionsAppropriate cell surface receptorIntracellular second messengerCell surface receptorsMulticellular organismsNutrient acquisitionStructural organizerCell signalingLarger speciesDistant cellsCellular responsesSecond messengerRecipient cellsNumerous signalsCell typesCell surfaceIndividual cellsEffector moleculesSurface receptorsCoordinated seriesSingle cellsDiffusible factorsOrganisms
2001
Cell Surface Glypicans Are Low-Affinity Endostatin Receptors
Karumanchi S, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai J, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen R, Lander A, Hagihara K, Yamaguchi Y, Sasisekharan R, Cantley L, Sukhatme V. Cell Surface Glypicans Are Low-Affinity Endostatin Receptors. Molecular Cell 2001, 7: 811-822. PMID: 11336704, DOI: 10.1016/s1097-2765(01)00225-8.Peer-Reviewed Original ResearchConceptsHeparan sulfate glycosaminoglycansPotent anti-angiogenic proteinCell surface proteoglycansBranching morphogenesisEndothelial cellsGenetic studiesGlypicansExpression cloningSurface proteoglycansAntisense experimentsCell surfaceAnti-angiogenic proteinEndothelial cell surfaceLow-affinity receptorsSulfate glycosaminoglycansEndostatin bindingCellsReceptorsMorphogenesisEndostatin activityCloningProteinEndostatinBindingProteoglycans