2014
Quantitative proteomics identification of potential protein biomarkers of early recovery after kidney transplant (591.5)
Williams K, Colangelo C, Stone K, Chung L, Abbott T, Belcher J, Marlier A, Cantley L, Parikh C. Quantitative proteomics identification of potential protein biomarkers of early recovery after kidney transplant (591.5). The FASEB Journal 2014, 28 DOI: 10.1096/fasebj.28.1_supplement.591.5.Peer-Reviewed Original ResearchKidney transplantUrine proteomeKidney transplant recipientsPotential urine biomarkersKidney transplant patientsDeceased donor kidneysDGF patientsGraft functionTransplant patientsTransplant recipientsSerum creatinineDonor kidneysUrine biomarkersUrine proteinEarly biomarkersEarly recoveryMass spectrometric-based approachesPotential protein biomarkersFirst weekIGFUrine samplesBiomarkersPatientsTransplantDGF
2000
Reactive Oxygen Species Expose Cryptic Epitopes Associated with Autoimmune Goodpasture Syndrome*
Kalluri R, Cantley L, Kerjaschki D, Neilson E. Reactive Oxygen Species Expose Cryptic Epitopes Associated with Autoimmune Goodpasture Syndrome*. Journal Of Biological Chemistry 2000, 275: 20027-20032. PMID: 10748075, DOI: 10.1074/jbc.m904549199.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnti-Glomerular Basement Membrane DiseaseAutoantibodiesBasement MembraneCollagenDose-Response Relationship, DrugEnzyme-Linked Immunosorbent AssayEpitopesFluorescent Antibody TechniqueHumansHydrogen PeroxideKidneyMiceMice, Inbred BALB CProtein Structure, TertiaryRatsReactive Oxygen SpeciesTime FactorsConceptsGoodpasture's syndromeReactive oxygen speciesGoodpasture epitopeType IV collagenRenal transplant recipientsIV collagenEffects of ROSTime-dependent fashionTransplant recipientsNeoantigen formationAutoantibody productionImmune activationAutoimmune diseasesHydrogen peroxide administrationAge-dependent deteriorationT cellsNon-collagenous globular domainsImmune systemEpitope diversityCryptic epitopesSyndromeAlport syndromeHeterologous antibodiesGoodpasture antibodyEpitopes