2021
Development and external validation of a diagnostic model for biopsy-proven acute interstitial nephritis using electronic health record data
Moledina DG, Eadon MT, Calderon F, Yamamoto Y, Shaw M, Perazella MA, Simonov M, Luciano R, Schwantes-An TH, Moeckel G, Kashgarian M, Kuperman M, Obeid W, Cantley LG, Parikh CR, Wilson FP. Development and external validation of a diagnostic model for biopsy-proven acute interstitial nephritis using electronic health record data. Nephrology Dialysis Transplantation 2021, 37: 2214-2222. PMID: 34865148, PMCID: PMC9755995, DOI: 10.1093/ndt/gfab346.Peer-Reviewed Original ResearchConceptsAcute interstitial nephritisInterstitial nephritisUrine biomarkersBiopsy-proven acute interstitial nephritisElectronic health record dataExternal validation cohortTypical clinical featuresBlood urea nitrogenTumor necrosis factorCharacteristic curve analysisHealth record dataExternal validationElectronic health recordsAIN diagnosisModest AUCsSerum creatinineCreatinine ratioKidney biopsyClinical featuresValidation cohortNecrosis factorUnrecognized casesInterleukin-9PatientsUrea nitrogen
2014
Quantitative proteomics identification of potential protein biomarkers of early recovery after kidney transplant (591.5)
Williams K, Colangelo C, Stone K, Chung L, Abbott T, Belcher J, Marlier A, Cantley L, Parikh C. Quantitative proteomics identification of potential protein biomarkers of early recovery after kidney transplant (591.5). The FASEB Journal 2014, 28 DOI: 10.1096/fasebj.28.1_supplement.591.5.Peer-Reviewed Original ResearchKidney transplantUrine proteomeKidney transplant recipientsPotential urine biomarkersKidney transplant patientsDeceased donor kidneysDGF patientsGraft functionTransplant patientsTransplant recipientsSerum creatinineDonor kidneysUrine biomarkersUrine proteinEarly biomarkersEarly recoveryMass spectrometric-based approachesPotential protein biomarkersFirst weekIGFUrine samplesBiomarkersPatientsTransplantDGF