2024
GP100 expression is variable in intensity in melanoma
Mann J, Hasson N, Su D, Adeniran A, Smalley K, Djureinovic D, Jilaveanu L, Schoenfeld D, Kluger H. GP100 expression is variable in intensity in melanoma. Cancer Immunology, Immunotherapy 2024, 73: 191. PMID: 39105816, PMCID: PMC11303354, DOI: 10.1007/s00262-024-03776-5.Peer-Reviewed Original ResearchConceptsGp100 expressionCutaneous melanomaTreatment of cutaneous melanomaAdvanced cutaneous melanomaT-cell engagersImprove patient selectionMetastatic melanomaUveal melanomaMetastatic samplesPatient selectionClinical trialsMelanomaQuantitative immunofluorescence methodGp100Improve outcomesImmunofluorescence methodTherapeutic intentDrugCellular productsExpressionTebentafuspImmunohistochemistry
2019
Comparative analysis of CEACAM1 expression in thin melanomas with and without regression
Nichita L, Zurac S, Bastian A, Stinga P, Nedelcu R, Brinzea A, Turcu G, Ion D, Jilaveanu L, Sticlaru L, Popp C, Cioplea M. Comparative analysis of CEACAM1 expression in thin melanomas with and without regression. Oncology Letters 2019, 17: 4149-4154. PMID: 30944609, PMCID: PMC6444332, DOI: 10.3892/ol.2019.10067.Peer-Reviewed Original ResearchCarcinoembryonic antigen-related cell adhesion molecule 1CEACAM1 expressionThin melanomasMelanoma cell invasionTumor cellsHomophilic interactionsAA-1Extracellular domainStructural roleNatural killer cell activityCell invasionCell adhesion molecule-1Key moleculesKiller cell activityNatural killer cellsDeep invasive frontAdhesion molecule-1Full lengthValuable modelCEACAM1 overexpressionDifferent clonesExpressionKiller cellsTumor immunityClones