2006
In Vivo Membrane Topology of Escherichia coli SecA ATPase Reveals Extensive Periplasmic Exposure of Multiple Functionally Important Domains Clustering on One Face of SecA*
Jilaveanu LB, Oliver DB. In Vivo Membrane Topology of Escherichia coli SecA ATPase Reveals Extensive Periplasmic Exposure of Multiple Functionally Important Domains Clustering on One Face of SecA*. Journal Of Biological Chemistry 2006, 282: 4661-4668. PMID: 17166834, DOI: 10.1074/jbc.m610828200.Peer-Reviewed Original ResearchConceptsSecA ATPaseEscherichia coli SecA ATPaseProtein translocation pathwayProtein-conducting channelRegion of SecABacterial plasma membraneMembrane-integrated stateTransport of proteinsSecA mutantSecA domainProtein translocationMembrane topologyMembrane cyclingSecA structureMembrane insertionTranslocation pathwayProtein cargoPlasma membraneSulfhydryl labelingN-domainSecAC-domainTrans sideChannel complexLabeling patternsSecA Dimer Cross-Linked at Its Subunit Interface Is Functional for Protein Translocation
Jilaveanu LB, Oliver D. SecA Dimer Cross-Linked at Its Subunit Interface Is Functional for Protein Translocation. Journal Of Bacteriology 2006, 188: 335-338. PMID: 16352850, PMCID: PMC1317605, DOI: 10.1128/jb.188.1.335-338.2006.Peer-Reviewed Original Research
2002
Monomeric Yeast PCNA Mutants Are Defective in Interacting with and Stimulating the ATPase Activity of RFC †
Ionescu CN, Shea KA, Mehra R, Prundeanu L, McAlear MA. Monomeric Yeast PCNA Mutants Are Defective in Interacting with and Stimulating the ATPase Activity of RFC †. Biochemistry 2002, 41: 12975-12985. PMID: 12390024, DOI: 10.1021/bi026029s.Peer-Reviewed Original ResearchConceptsReplication factor CMutant PCNAsDNA clampDNA damaging agent methylmethane sulfonateDNA polymerase accessory proteinMutant PCNA proteinsAgent methylmethane sulfonatePolymerase accessory proteinsProtein-protein interactionsWild-type subunitsSingle amino acid substitutionDNA repair pathwaysATPase activityE. coliAmino acid substitutionsYeast PCNAPCNA mutantsClamp loaderPCNA functionPCNA trimerBeta clampAccessory proteinsRepair pathwaysMethylmethane sulfonateAdjacent subunits