2006
Language lateralization and the role of the fusiform gyrus in semantic processing in young children
Balsamo LM, Xu B, Gaillard WD. Language lateralization and the role of the fusiform gyrus in semantic processing in young children. NeuroImage 2006, 31: 1306-1314. PMID: 16545581, DOI: 10.1016/j.neuroimage.2006.01.027.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBrain MappingCerebral CortexChildChild, PreschoolDecision MakingDominance, CerebralFemaleFrontal LobeHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMotor CortexNeuropsychological TestsOxygenPsychomotor PerformanceReaction TimeReadingSemanticsSpeech PerceptionConceptsSemantic processingFusiform gyrusEarly word recognition processesAuditory semantic processingWord recognition processesAdult language processingSemantic decision taskSemantic category decisionsLeft fusiform gyrusPrevious neuroimaging findingsLeft-lateralized patternYoung childrenPattern of activationLanguage comprehensionDecision taskCategory decisionsTask accuracyTask difficultyLanguage developmentLanguage lateralizationFMRI techniquesLanguage processingBrain regionsCortical regionsNeuroimaging findings
2004
fMRI language task panel improves determination of language dominance
Gaillard WD, Balsamo L, Xu B, McKinney C, Papero PH, Weinstein S, Conry J, Pearl PL, Sachs B, Sato S, Vezina LG, Frattali C, Theodore WH. fMRI language task panel improves determination of language dominance. Neurology 2004, 63: 1403-1408. PMID: 15505156, DOI: 10.1212/01.wnl.0000141852.65175.a7.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrain MappingCerebral CortexCerebrovascular CirculationChildDominance, CerebralEpilepsyFemaleHumansLanguageLanguage TestsMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsPreoperative CareReproducibility of ResultsSpeech PerceptionTemporal LobeVerbal BehaviorConceptsIntracarotid amobarbital testPanel of tasksLanguage dominanceSingle taskEpilepsy patientsFMRI language paradigmsHemisphere language dominancePatients ages 12Temporal lobe epilepsyPartial epilepsy patientsPresurgical epilepsy patientsAuditory comprehensionFMRI taskVerbal fluencyLanguage tasksLanguage lateralityBilateral activationLanguage lateralizationT fMRILanguage areasNondiagnostic findingsLobe epilepsyAmobarbital testLanguage paradigmsSingle paradigm
2003
Auditory comprehension of language in young children
Ahmad Z, Balsamo L, Sachs B, Xu B, Gaillard W. Auditory comprehension of language in young children. Neurology 2003, 60: 1598-1605. PMID: 12771248, DOI: 10.1212/01.wnl.0000059865.32155.86.Peer-Reviewed Original ResearchConceptsAuditory comprehensionTemporal gyrusYoung childrenLeft middle temporal gyrusAuditory language processingSuperior temporal sulcusRight-handed childrenMiddle temporal gyrusSuperior temporal gyrusLanguage fMRI studyTemporal sulcusLateralized activationFMRI studyAngular gyrusLanguage organizationIndividual subject dataLanguage processingTemporal regionsBrain regionsControl conditionFrontal lobeAge 5GyrusSignificant activationFMRIDevelopmental aspects of language processing: fMRI of verbal fluency in children and adults
Gaillard WD, Sachs BC, Whitnah JR, Ahmad Z, Balsamo LM, Petrella JR, Braniecki SH, McKinney CM, Hunter K, Xu B, Grandin CB. Developmental aspects of language processing: fMRI of verbal fluency in children and adults. Human Brain Mapping 2003, 18: 176-185. PMID: 12599275, PMCID: PMC6871939, DOI: 10.1002/hbm.10091.Peer-Reviewed Original ResearchConceptsLaterality of activationSemantic verbal fluencyVerbal fluencyFluency taskFrontal gyrusSemantic verbal fluency taskInferior frontal gyrusSemantic fluency taskVerbal fluency taskMiddle frontal gyrusTask testingDevelopmental differencesLanguage processingFluencyBrain areasDevelopmental aspectsAge 7 yearsFMRIInterest approachBOLD fMRISPM 99GyrusActivation mapsChildrenAdultsfMRI identifies regional specialization of neural networks for reading in young children
Gaillard WD, Balsamo LM, Ibrahim Z, Sachs BC, Xu B. fMRI identifies regional specialization of neural networks for reading in young children. Neurology 2003, 60: 94-100. PMID: 12525725, DOI: 10.1212/wnl.60.1.94.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusFrontal gyrusTemporal-occipital junctionMiddle temporal gyrusYoung childrenSupplementary motor areaFusiform gyrusLanguage networkTemporal gyrusOccipital junctionLanguage lateralizationNative EnglishEarly readersWernicke's areaNeural networkMotor areaBrain regionsCognitive networksAge 6Prominent activationGyrusFMRIChildren 7Interest approachBOLD technique
2002
Neuroimaging Reveals Automatic Speech Coding during Perception of Written Word Meaning
Xu B, Grafman J, Gaillard WD, Spanaki M, Ishii K, Balsamo L, Makale M, Theodore WH. Neuroimaging Reveals Automatic Speech Coding during Perception of Written Word Meaning. NeuroImage 2002, 17: 859-870. PMID: 12377160, DOI: 10.1006/nimg.2002.1215.Peer-Reviewed Original ResearchConceptsSemantic processingWord meaningsVisual word perceptionMultiple cognitive tasksMechanisms of readingButton-press responseFunctional magnetic resonance imaging (fMRI) techniquesBehavioral response measuresSignificant bilateral activationPhonological recodingPhonological tasksWord perceptionWord readingLetter stringsCognitive tasksSemantic tasksNeural basisNeuroimaging sessionSpeech soundsBaseline taskPhonological processesNeural responsesVisual stimuliActive processingSpeech codeA Functional Magnetic Resonance Imaging Study of Left Hemisphere Language Dominance in Children
Balsamo LM, Xu B, Grandin CB, Petrella JR, Braniecki SH, Elliott TK, Gaillard WD. A Functional Magnetic Resonance Imaging Study of Left Hemisphere Language Dominance in Children. JAMA Neurology 2002, 59: 1168-1174. PMID: 12117366, DOI: 10.1001/archneur.59.7.1168.Peer-Reviewed Original ResearchConceptsFrontal gyrusTemporal gyrusLanguage dominanceFunctional magnetic resonance imaging studyLeft hemisphere language dominanceFunctional magnetic resonance imagingAuditory language taskStrong left lateralizationLeft inferior temporal gyrusInferior frontal gyrusFunctional magnetic resonanceMiddle temporal gyrusMiddle frontal gyrusHemisphere language dominanceInferior temporal gyrusMagnetic resonance imaging studyResonance imaging studyReceptive languageHemisphere lateralizationLeft lateralizationAreas of activationLanguage tasksLeft fusiformGreater activationHemispheric lateralization
2001
Cortical localization of reading in normal children
Gaillard WD, Pugliese M, Grandin CB, Braniecki SH, Kondapaneni P, Hunter K, Xu B, Petrella JR, Balsamo L, Basso G. Cortical localization of reading in normal children. Neurology 2001, 57: 47-54. PMID: 11445627, DOI: 10.1212/wnl.57.1.47.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusFrontal gyrusTemporal gyrusLeft inferior frontal gyrusLeft middle temporal gyrusBrain regionsLanguage processing areasBlood oxygen level-dependent fMRIMiddle temporal gyrusDorsolateral prefrontal cortexSuperior temporal gyrusMiddle frontal gyrusLeft-sided lateralizationLevel-dependent fMRINaming TaskLanguage dominanceRegion activationText paradigmPrefrontal cortexCognitive functionNative EnglishMidfrontal gyrusTemporal cortexLate childhoodFMRI