2016
Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study
Kunin-Batson AS, Lu X, Balsamo L, Graber K, Devidas M, Hunger SP, Carroll WL, Winick NJ, Mattano LA, Maloney KW, Kadan-Lottick NS. Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study. Cancer 2016, 122: 1608-1617. PMID: 27028090, PMCID: PMC4860039, DOI: 10.1002/cncr.29946.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsAnxietyChildChild, PreschoolDepressionFamily RelationsFemaleHumansLongitudinal StudiesMalePrecursor Cell Lymphoblastic Leukemia-LymphomaPrevalenceProspective StudiesRandomized Controlled Trials as TopicConceptsAcute lymphoblastic leukemiaCompletion of treatmentGreater riskEmotional-behavioral functioningChildren's Oncology Group protocolsChildhood acute lymphoblastic leukemiaAdjusted longitudinal analysesCompletion of chemotherapyDepressive symptoms 6 monthsSymptoms 6 monthsEmotional distressElevated anxiety scoresAnxiety 1 monthStandardized rating scalesElevated depression scoresChildren's emotional-behavioral functioningLymphoblastic leukemiaPredictors of anxietySocial support copingMeasures of copingDepressive symptomsGeneral populationDepression scoresPsychosocial interventionsEarly screening
2015
Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331
Mitchell H, Lu X, Myers RM, Sung L, Balsamo LM, Carroll WL, Raetz E, Loh ML, Mattano LA, Winick NJ, Devidas M, Hunger SP, Maloney K, Kadan-Lottick N. Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331. International Journal Of Cancer 2015, 138: 332-339. PMID: 26235006, PMCID: PMC5138856, DOI: 10.1002/ijc.29708.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsChildChild, PreschoolFemaleHumansLongitudinal StudiesMalePrecursor Cell Lymphoblastic Leukemia-LymphomaProspective StudiesQuality of LifeSurveys and QuestionnairesConceptsStandard-risk acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLife Inventory 4.0 Generic Core ScalesChildren's Oncology Group studyHRQoL 1 monthMean PedsQL scoresYears of therapyHealth-related qualityEnd of inductionHigh cure ratesGeneric Core ScalesSocial functioningRepeated-measures analysisTherapy completionTherapeutic trialsCure ratePediatric QualityPedsQL scoresConsiderable impairmentLongitudinal assessmentDiagnosisTherapyMonthsGroup studyChemotherapy-only treatment effects on long-term neurocognitive functioning in childhood ALL survivors: a review and meta-analysis
Iyer NS, Balsamo LM, Bracken MB, Kadan-Lottick NS. Chemotherapy-only treatment effects on long-term neurocognitive functioning in childhood ALL survivors: a review and meta-analysis. Blood 2015, 126: 346-353. PMID: 26048910, DOI: 10.1182/blood-2015-02-627414.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsBrain NeoplasmsChildCognition DisordersHumansPrecursor Cell Lymphoblastic Leukemia-LymphomaSurvival RateSurvivorsConceptsLong-term neurocognitive functioningAcute lymphoblastic leukemiaCranial radiationNeurocognitive functioningIntelligence quotientChildhood acute lymphoblastic leukemiaContinuous first remissionSurvivors of childhoodDatabase of AbstractsConfidence intervalsHealthy control groupStandard deviation scoreFine motor domainNeurocognitive domainsReviews of EffectsMEDLINE/PubMedFirst remissionFull-scale intelligence quotientPerformance intelligence quotientLymphoblastic leukemiaInformation processing speedDeviation scoreSD scoreModerate impairmentMultiple neurocognitive domains
2014
A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia
Myers RM, Balsamo L, Lu X, Devidas M, Hunger SP, Carroll WL, Winick NJ, Maloney KW, Kadan‐Lottick N. A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia. Cancer 2014, 120: 1417-1425. PMID: 24473774, PMCID: PMC4319360, DOI: 10.1002/cncr.28578.Peer-Reviewed Original ResearchMeSH KeywordsAggressionAntineoplastic Combined Chemotherapy ProtocolsAnxietyAsparaginaseBehaviorChildChild, PreschoolCohort StudiesCyclophosphamideDepressionDexamethasoneEmotionsFemaleHumansLongitudinal StudiesMalePolyethylene GlycolsPrecursor Cell Lymphoblastic Leukemia-LymphomaProspective StudiesPsychomotor AgitationVincristineConceptsStandard-risk acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaUnhealthy family functioningHispanic ethnicityChildren's Oncology Group protocolsChildhood acute lymphoblastic leukemiaClinical rangeSubpopulation of patientsWorse physical functioningMore childrenFirst yearCoping Health InventoryCohort studyProspective studyRisk factorsPhysical functioningFamily functioningHealth InventoryFamily Assessment DevicePopulation normsMonthsFunctioning ScaleDepressionGroup protocol