2014
Somatic insulin signaling regulates a germline starvation response in Drosophila egg chambers
Burn KM, Shimada Y, Ayers K, Vemuganti S, Lu F, Hudson A, Cooley L. Somatic insulin signaling regulates a germline starvation response in Drosophila egg chambers. Developmental Biology 2014, 398: 206-217. PMID: 25481758, PMCID: PMC4340711, DOI: 10.1016/j.ydbio.2014.11.021.Peer-Reviewed Original ResearchConceptsDrosophila insulin-like peptidesEgg chambersStarvation responseBody organizationDrosophila egg chamberMotor protein dyneinNutrient-rich conditionsPoor nutrient availabilityInsulin-like peptidesProcessing bodiesDrosophila femalesGermline cellsP-bodiesNutrient availabilityDynein activityInsulin signalingProgeny survivalInsulin pathwayKinesin activityFollicle cellsMicrotubulesStarvationBovine insulinPotential mechanismsProtective response
1998
Apoptosis in late stage Drosophila nurse cells does not require genes within the H99 deficiency
Foley K, Cooley L. Apoptosis in late stage Drosophila nurse cells does not require genes within the H99 deficiency. Development 1998, 125: 1075-1082. PMID: 9463354, DOI: 10.1242/dev.125.6.1075.Peer-Reviewed Original ResearchConceptsEgg chambersNurse cellsDNA fragmentationDrosophila nurse cellsMutant egg chambersDrosophila egg chamberOvarian expression patternsDrosophila apoptosisGermline clonesHead involutionCytoplasm transportPositive regulatorRegulatory genesStage 13Cytoplasm transferApoptotic vesiclesCytoplasmic factorsNegative regulatorExpression patternsWild typeGenesFragmented DNAOogenesisApoptosisStage 12