2013
Protein Equilibration Through Somatic Ring Canals in Drosophila
McLean PF, Cooley L. Protein Equilibration Through Somatic Ring Canals in Drosophila. Science 2013, 340: 1445-1447. PMID: 23704373, PMCID: PMC3819220, DOI: 10.1126/science.1234887.Peer-Reviewed Original ResearchConceptsRing canalsLarval imaginal discsDrosophila ovaryClone boundariesImaginal discsIncomplete cytokinesisIntercellular communicationCytoplasmic contentsFollicle cellsIntercellular bridgesTissue biologyProtein expressionConnected cellsDrosophilaCytokinesisCellsBiologyProteinTissueExpressionOvaries
2011
Intercellular protein movement in syncytial Drosophila follicle cells
Airoldi SJ, McLean PF, Shimada Y, Cooley L. Intercellular protein movement in syncytial Drosophila follicle cells. Journal Of Cell Science 2011, 124: 4077-4086. PMID: 22135360, PMCID: PMC3244987, DOI: 10.1242/jcs.090456.Peer-Reviewed Original ResearchConceptsImaginal disc cellsRing canalsFollicle cellsPavarotti kinesin-like proteinDrosophila follicle cellsIntercellular protein movementEgg chamber developmentKinesin-like proteinMitotic cleavage furrowsLive-cell confocal microscopyDisc cellsBroad functional significanceDrosophila germlineGermline cellsCytoplasmic proteinsSomatic cellsProtein movementCleavage furrowFunctional significanceChamber developmentSyncytial organizationConfocal microscopyGermlineProteinCellsReversible response of protein localization and microtubule organization to nutrient stress during Drosophila early oogenesis
Shimada Y, Burn KM, Niwa R, Cooley L. Reversible response of protein localization and microtubule organization to nutrient stress during Drosophila early oogenesis. Developmental Biology 2011, 355: 250-262. PMID: 21570389, PMCID: PMC3118931, DOI: 10.1016/j.ydbio.2011.04.022.Peer-Reviewed Original ResearchConceptsEgg chambersNutrient stressIntercellular transportMT reorganizationNutrient availabilityNurse cellsPutative RNA binding proteinMT-dependent mannerRNA binding proteinYpsilon SchachtelDrosophila oogenesisProcessing bodiesProtein localizationEarly oogenesisNutrient deprivationMicrotubule organizationMetabolic checkpointCytoplasmic componentsAnimal oocytesStress responseYolk uptakeBinding proteinPrevitellogenic stageOogenesisIndependent mechanisms
2007
Jagunal is required for reorganizing the endoplasmic reticulum during Drosophila oogenesis
Lee S, Cooley L. Jagunal is required for reorganizing the endoplasmic reticulum during Drosophila oogenesis. Journal Of Cell Biology 2007, 176: 941-952. PMID: 17389229, PMCID: PMC2064080, DOI: 10.1083/jcb.200701048.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceCaenorhabditis elegansCell DifferentiationConserved SequenceCytoplasmic StreamingDrosophila melanogasterDrosophila ProteinsEndoplasmic ReticulumExocytosisGolgi ApparatusMembrane ProteinsMicroscopy, Electron, TransmissionMolecular Sequence DataOocytesOogenesisProtein TransportSequence Homology, Amino AcidSequence Homology, Nucleic AcidTransport VesiclesZebrafishConceptsVesicular trafficMembrane trafficEndoplasmic reticulumER reorganizationER membrane proteinsDrosophila melanogaster oocytesDrosophila oogenesisMembrane proteinsOocyte endoplasmic reticulumLateral membranesER clusteringReticulumImportant mechanismVitellogenesisOocytesOogenesisEndocytosisReorganizationProteinMembraneCells
2004
Flytrap, a database documenting a GFP protein‐trap insertion screen in Drosophila melanogaster
Kelso RJ, Buszczak M, Quiñones AT, Castiblanco C, Mazzalupo S, Cooley L. Flytrap, a database documenting a GFP protein‐trap insertion screen in Drosophila melanogaster. Nucleic Acids Research 2004, 32: d418-d420. PMID: 14681446, PMCID: PMC308749, DOI: 10.1093/nar/gkh014.Peer-Reviewed Original ResearchConceptsProtein localizationInsertion linesDrosophila melanogasterGFP fusion proteinTransposable element insertionsCellular component ontologyGene Ontology ConsortiumTransposable P elementsInverse PCR productsGene intronsArtificial exonElement insertionsGenomic DNAFusion proteinFlytrapMelanogasterComponent ontologyP elementsStages of developmentType of tissueLocalizationFlyBaseIntronsExonsGenes