2007
Mononuclear muscle cells in Drosophila ovaries revealed by GFP protein traps
Hudson AM, Petrella LN, Tanaka AJ, Cooley L. Mononuclear muscle cells in Drosophila ovaries revealed by GFP protein traps. Developmental Biology 2007, 314: 329-340. PMID: 18199432, PMCID: PMC2293129, DOI: 10.1016/j.ydbio.2007.11.029.Peer-Reviewed Original ResearchConceptsMuscle specificationEpithelial sheath cellsMyoblast fusionSheath cellsProtein trapSarcomere organizationFLP/FRT systemMononuclear muscle cellsMuscle cellsDrosophila ovaryGonadal mesodermGenetic mosaicsKey genesTrap linesFRT systemGenetic analysisHuman muscle physiologySomatic musclesVisceral musclesSingle nucleusClonal analysisFemale reproductive systemMuscle physiologyEpithelial sheathModel system
2005
Drosophila myosin V is required for larval development and spermatid individualization
Mermall V, Bonafé N, Jones L, Sellers JR, Cooley L, Mooseker MS. Drosophila myosin V is required for larval development and spermatid individualization. Developmental Biology 2005, 286: 238-255. PMID: 16126191, DOI: 10.1016/j.ydbio.2005.07.028.Peer-Reviewed Original ResearchConceptsInvestment conesLarval developmentClass V myosinsIndividualization complexSpermatid individualizationCytological defectsTruncation alleleVesicular trafficRNA transportActin structuresLarval tissuesMutant animalsMature spermSperm nucleiMyoVSpermatid maturationMolecular motorsMyosin VMechanochemical couplingDetectable defectsV geneMicrotubulesIndividual membranesActinSpermatogenesis
2000
Physical and genetic interaction of filamin with presenilin in Drosophila
Guo Y, Zhang S, Sokol N, Cooley L, Boulianne G. Physical and genetic interaction of filamin with presenilin in Drosophila. Journal Of Cell Science 2000, 113: 3499-3508. PMID: 10984440, DOI: 10.1242/jcs.113.19.3499.Peer-Reviewed Original ResearchMeSH KeywordsAlternative SplicingAlzheimer DiseaseAmino Acid SequenceAnimalsBlotting, WesternCarrier ProteinsCloning, MolecularContractile ProteinsDrosophila melanogasterEmbryo, NonmammalianFemaleFilaminsGene Expression Regulation, DevelopmentalHumansInsect ProteinsLarvaMaleMembrane ProteinsMicrofilament ProteinsMolecular Sequence DataPresenilin-1Presenilin-2Protein BindingProtein IsoformsProtein Structure, TertiaryRecombinant Fusion ProteinsRNA, MessengerTwo-Hybrid System TechniquesConceptsN-terminal actin-binding domainOverall amino acid identityOverexpression of presenilinFamilial Alzheimer's diseaseTransmembrane domain proteinActin-binding domainAmino acid identityLarge hydrophilic loopDrosophila filaminDomain proteinsGenetic interactionsAlternative splicingHydrophilic loopAcid identityTerminal domainDrosophilaHuman filaminChromosome 3Spliced formsFilaminAdult phenotypeLoop regionPresenilinNovel familyLong form