2014
Poorer Prognosis of African-American Patients With Mycosis Fungoides: An Analysis of the SEER Dataset, 1988 to 2008
Nath SK, Yu JB, Wilson LD. Poorer Prognosis of African-American Patients With Mycosis Fungoides: An Analysis of the SEER Dataset, 1988 to 2008. Clinical Lymphoma Myeloma & Leukemia 2014, 14: 419-423. PMID: 24508350, PMCID: PMC4081527, DOI: 10.1016/j.clml.2013.12.018.Peer-Reviewed Original ResearchConceptsDisease-specific survivalAA raceRT utilizationRadiation therapyOverall survivalTumor stageMultivariate analysisInitial treatment modalityWorse overall survivalAfrican American patientsPublic-use databaseClinical factorsTumor RegistryAA patientsFemale patientsMycosis fungoidesWorse prognosisPoor prognosisFemale sexTreatment modalitiesAdvanced agePoor survivalPoorer PrognosisPatientsMedical care
2000
Experience with total skin electron beam therapy in combination with extracorporeal photopheresis in the management of patients with erythrodermic (T4) mycosis fungoides
Wilson L, Jones G, Kim D, Rosenthal D, Christensen I, Edelson R, Heald P, Kacinski B. Experience with total skin electron beam therapy in combination with extracorporeal photopheresis in the management of patients with erythrodermic (T4) mycosis fungoides. Journal Of The American Academy Of Dermatology 2000, 43: 54-60. PMID: 10863224, DOI: 10.1067/mjd.2000.105510.Peer-Reviewed Original ResearchConceptsTotal skin electron beam radiationCause-specific survivalProgression-free survivalErythrodermic mycosis fungoidesDisease-free survivalExtracorporeal photopheresisPrognosis of patientsMycosis fungoidesOverall survivalTotal skin electron beam therapyComplete response ratePercent of patientsManagement of patientsMonths of completionCancer Care OntarioTreatment 2 daysElectron beam therapyHematologic involvementComplete respondersStage IVAMedian ageCox regressionPatientsTherapeutic RadiologyYale University School
1999
The changing survival of patients with mycosis fungoides
Jones G, Wilson L. The changing survival of patients with mycosis fungoides. Cancer 1999, 86: 191-193. PMID: 10391580, DOI: 10.1002/(sici)1097-0142(19990701)86:1<191::aid-cncr26>3.0.co;2-e.Peer-Reviewed Original ResearchTotal skin electron radiation for patients with erythrodermic cutaneous T‐cell lymphoma (mycosis fungoides and the Sézary syndrome)
Jones G, Rosenthal D, Wilson L. Total skin electron radiation for patients with erythrodermic cutaneous T‐cell lymphoma (mycosis fungoides and the Sézary syndrome). Cancer 1999, 85: 1985-1995. PMID: 10223240, DOI: 10.1002/(sici)1097-0142(19990501)85:9<1985::aid-cncr16>3.0.co;2-o.Peer-Reviewed Original ResearchConceptsErythrodermic mycosis fungoidesBlood involvementMycosis fungoidesCutaneous remissionSpecific survivalStage IIIErythrodermic cutaneous T-cell lymphomaTotal skin electron beam radiationMedian cause-specific survivalCutaneous T-cell lymphomaMedian overall survivalStage IVB diseaseCause-specific survivalStage III diseaseMedian radiation doseMedian treatment timeT-cell lymphomaToxicity of radiationIVB diseaseAdjuvant therapyStage IVAVisceral involvementModality therapyOverall survivalLymph nodesEvaluation of T-cell receptor gene rearrangements in patients with recurrent patch/plaque (T2) CTCL (mycosis fungoides).
Thayu M, Tallini G, Glusac E, Kacinski B, Wilson L. Evaluation of T-cell receptor gene rearrangements in patients with recurrent patch/plaque (T2) CTCL (mycosis fungoides). The Yale Journal Of Biology And Medicine 1999, 72: 365-75. PMID: 11138932, PMCID: PMC2579043.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyDisease-free intervalMycosis fungoidesPolymerase chain reactionSkin biopsiesMedian disease-free intervalCutaneous T-cell lymphomaT-cell receptor gene rearrangementsDominant TCR clonesT-cell receptor gamma gene rearrangementEvaluation of patientsTissue samplesIdentification of patientsT-cell lymphomaGene rearrangementsReceptor gene rearrangementsGamma gene rearrangementsRecurrent mycosis fungoidesElectron beam therapyDominant TCRMF patientsTCR analysisTCR clonesMalignant lymphocytesT lymphocytes
1998
Local Superficial Radiotherapy in the Management of Minimal Stage IA Cutaneous T-Cell Lymphoma (Mycosis Fungoides)
Wilson L, Kacinski B, Jones G. Local Superficial Radiotherapy in the Management of Minimal Stage IA Cutaneous T-Cell Lymphoma (Mycosis Fungoides). International Journal Of Radiation Oncology • Biology • Physics 1998, 40: 109-115. PMID: 9422565, DOI: 10.1016/s0360-3016(97)00553-1.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaStage IA mycosis fungoidesT-cell lymphomaAdjuvant therapyLocal controlMycosis fungoidesSuperficial radiationSuperficial radiotherapyDistant skin sitesMedian fraction numberMedian surface doseComplete response rateExcellent local controlDry desquamationPrior therapyHematologic toxicityPrior radiationDistant failurePersistent diseaseMedian ageCutaneous malignanciesPathologic documentationSurface doseMild erythemaPatients
1997
Total skin electron beam therapy followed by adjuvant psoralen/ultraviolet-A light in the management of patients with T1 and T2 cutaneous T-cell lymphoma (mycosis fungoides)
Quirós P, Jones G, Kacinski B, Braverman I, Heald P, Edelson R, Wilson L. Total skin electron beam therapy followed by adjuvant psoralen/ultraviolet-A light in the management of patients with T1 and T2 cutaneous T-cell lymphoma (mycosis fungoides). International Journal Of Radiation Oncology • Biology • Physics 1997, 38: 1027-1035. PMID: 9276369, DOI: 10.1016/s0360-3016(97)00127-2.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyDisease-free survivalT2 patientsCrude relapse rateAdjuvant therapyOverall survivalElectron beam therapyRelapse rateEntire cohortMedian disease-free survivalCutaneous T-cell lymphomaBeam therapySalvage of recurrencesAdjuvant systemic therapyEarly-stage patientsManagement of patientsT-cell lymphomaTopical nitrogen mustardDays/weekCombination of therapiesGy/dayTreatments/weekPUVA patientsMedian followSalvage therapyMycosis Fungoides and Total Skin Electron Beam Radiation
Jones G, Wilson L, Kurzrock R, Diamandidou E, >Ha C, Cohen P. Mycosis Fungoides and Total Skin Electron Beam Radiation. Blood 1997, 89: 3062-3064. PMID: 9108429, DOI: 10.1182/blood.v89.8.3062.Peer-Reviewed Original Research
1996
Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma
Wilson L, Quiros P, Kolenik S, Heald P, Braverman I, Edelson R, Kacinski B. Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma. Journal Of The American Academy Of Dermatology 1996, 35: 69-73. PMID: 8682967, DOI: 10.1016/s0190-9622(96)90499-5.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyCutaneous T-cell lymphomaRecurrent cutaneous T-cell lymphomaComplete responseT-cell lymphomaElectron beam therapySecond courseMedian disease-free intervalThird courseAdditional coursesBeam therapyDisease-free intervalTreatment of patientsAcceptable risk profileForm of therapyMedian doseMedian survivalMild erythemaPatientsInitial courseTherapyVariety of modalitiesRisk profileEntire groupLocalized radiationExtent of skin involvement as a prognostic indicator of disease free and overall survival of patients with T3 cutaneous T‐cell lymphoma treated with total skin electron beam radiation therapy
Quiros P, Kacinski B, Wilson L. Extent of skin involvement as a prognostic indicator of disease free and overall survival of patients with T3 cutaneous T‐cell lymphoma treated with total skin electron beam radiation therapy. Cancer 1996, 77: 1912-1917. PMID: 8646693, DOI: 10.1002/(sici)1097-0142(19960501)77:9<1912::aid-cncr23>3.0.co;2-1.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Surface AreaChemotherapy, AdjuvantCohort StudiesDisease-Free SurvivalFemaleFollow-Up StudiesHumansLymphoma, T-Cell, CutaneousMaleMiddle AgedNeoplasm Recurrence, LocalPrognosisRadiotherapy DosageRadiotherapy, High-EnergyRemission InductionRetrospective StudiesSkinSkin NeoplasmsSurvival RateConceptsTotal skin electron beam therapyCutaneous T-cell lymphomaComplete clinical responseOverall survivalSkin involvementT-cell lymphomaMedian DFSPrognostic indicatorTotal skin electron beam radiation therapyToxicity of therapyElectron beam radiation therapyBeam radiation therapyTotal skin surfaceElectron beam therapyFree survivalClinical responsePrognostic significanceTumor nodulesRadiation therapyPatientsPatient recordsTherapyDiseaseBeam therapyMonths
1995
Systemic chemotherapy and extracorporeal photochemotherapy for T3 and T4 cutaneous T-cell lymphoma patients who have achieved a complete response to total skin electron beam therapy
Wilson L, Licata A, Braverman I, Edelson R, Heald P, Feldman A, Kacinski B. Systemic chemotherapy and extracorporeal photochemotherapy for T3 and T4 cutaneous T-cell lymphoma patients who have achieved a complete response to total skin electron beam therapy. International Journal Of Radiation Oncology • Biology • Physics 1995, 32: 987-995. PMID: 7607973, DOI: 10.1016/0360-3016(95)00073-8.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyDoxorubicin/cyclophosphamideCutaneous T-cell lymphoma patientsAdjuvant doxorubicin/cyclophosphamideT-cell lymphoma patientsExtracorporeal photochemotherapyComplete responseOverall survivalAdjuvant therapyElectron beam therapyAdjuvant regimenFree survivalCTCL patientsLymphoma patientsBeam therapyAddition of chemotherapyAdvanced stage CTCLClinical complete responseSystemic adjuvant therapyGood partial responseSignificant survival benefitBetter overall survivalRelapse-free survivalSoles of feetNontoxic regimen