2020
High frequency of p16 and SOX10 coexpression but not androgen receptor expression in triple-negative breast cancers
Yoon EC, Wilson P, Zuo T, Pinto M, Cole K, Harigopal M. High frequency of p16 and SOX10 coexpression but not androgen receptor expression in triple-negative breast cancers. Human Pathology 2020, 102: 13-22. PMID: 32565323, DOI: 10.1016/j.humpath.2020.06.004.Peer-Reviewed Original ResearchConceptsTriple-negative breast cancerNon-TNBC casesFrequency of p16TNBC casesAndrogen receptorBreast cancerTissue microarrayAggressive clinical courseAndrogen receptor expressionInvasive ductal carcinomaHistologic grade 3Basal-like breast cancer subtypeNovel prognostic markerBreast cancer subtypesExpression of p16Clinical courseCytokeratin 5/6Ductal carcinomaPrognostic markerReceptor expressionRoutine biomarkersSignificant statistical differenceClinical dataGrade 3Cancer subtypes
2018
Strong androgen receptor expression can aid in distinguishing GATA3+ metastases
Boto A, Harigopal M. Strong androgen receptor expression can aid in distinguishing GATA3+ metastases. Human Pathology 2018, 75: 63-70. PMID: 29408697, DOI: 10.1016/j.humpath.2018.01.024.Peer-Reviewed Original ResearchConceptsGATA3-positive tumorsAndrogen receptor expressionBreast originMetastatic settingUrothelial originAR expressionAR stainingAndrogen receptorReceptor expressionBreast cancerUnknown originBreast cancer tissue microarrayMarker of breastStrong AR expressionCancer tissue microarrayMammaglobin expressionUrothelial carcinomaLobular carcinomaProgesterone receptorEstrogen receptorTissue microarrayMammary originCarcinomaGATA3 expressionGATA3