2019
Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures
Datta R, Wang T, Zhu M, Dembry LM, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures. Infection Control And Hospital Epidemiology 2019, 40: 470-472. PMID: 30821230, PMCID: PMC6482377, DOI: 10.1017/ice.2019.22.Peer-Reviewed Original ResearchConceptsUrinary tract infectionIncidence rate ratiosAdvanced cancer patientsAsymptomatic bacteriuriaCancer patientsAntimicrobial therapySymptomatic urinary tract infectionPotential urinary tract infectionTract infectionsInappropriate therapyAntimicrobial daysComfort measuresBacteriuriaCandiduriaCFU/mLPatientsTherapyRate ratioMLInfectionDesign and analysis of longitudinal trials of antimicrobial use at the end of life: to give or not to give?
Juthani-Mehta M, Allore HG. Design and analysis of longitudinal trials of antimicrobial use at the end of life: to give or not to give? Therapeutic Advances In Drug Safety 2019, 10: 2042098618820210. PMID: 30800269, PMCID: PMC6378640, DOI: 10.1177/2042098618820210.Peer-Reviewed Original ResearchTerminal cancer patientsAntimicrobial useEnd of lifePalliative careCancer patientsLongitudinal trialBurden of medicationsCessation of medicationHealth literacy interventionsAntimicrobial therapyAntimicrobial prescribingHealth literacyTrial designComparative trial designTrial dataTrial periodMedicationsPatientsTrialsCareLongitudinal modelingLiteracy interventionsPrescribingTherapyInfection
2018
Increased Fluoroquinolone-Susceptibility and Preserved Nitrofurantoin-Susceptibility among Escherichia coli Urine Isolates from Women Long-Term Care Residents: A Brief Report
Datta R, Advani S, Rink A, Bianco L, Van Ness PH, Quagliarello V, Juthani-Mehta M. Increased Fluoroquinolone-Susceptibility and Preserved Nitrofurantoin-Susceptibility among Escherichia coli Urine Isolates from Women Long-Term Care Residents: A Brief Report. Open Access Journal Of Gerontology & Geriatric Medicine 2018, 4: 555636. PMID: 30465048, PMCID: PMC6241532, DOI: 10.19080/oajggm.2018.04.555636.Peer-Reviewed Original ResearchLong-term care residentsUrinary tract infectionUrine isolatesCare residentsTract infectionsUncomplicated urinary tract infectionsLong-term care facilitiesTrimethoprim/sulfamethoxazoleEmpiric therapyCommon indicationOptimal therapyUrine cultureUrinary isolatesAntimicrobial therapyClinical trialsNitrofurantoin susceptibilityCare facilitiesFluoroquinolone susceptibilityAntimicrobial susceptibilityPredominant organismTherapyInfectionCefazolinIsolatesBacterial isolatesFrequency of Infection during Fever Episodes among Long-Term Care Residents
Datta R, Advani S, Rink A, Bianco L, Van Ness PH, Quagliarello V, Juthani-Mehta M. Frequency of Infection during Fever Episodes among Long-Term Care Residents. Journal Of Gerontology & Geriatric Research 2018, 7: 1-2. PMID: 30197840, PMCID: PMC6128293, DOI: 10.4172/2167-7182.1000467.Peer-Reviewed Original ResearchLong-term care residentsLong-term care facilitiesFever episodesFrequency of infectionCare residentsCare facilitiesCase series analysisAdverse event surveillanceOlder adult womenCranberry capsulesMedian ageRandomized trialsSurveillance definitionsProvider assessmentTotal infectionsAdult womenInfectionOlder adultsEvent surveillanceWomenEpisodesTwo-thirdsResidentsPyuriaBacteriuria
2017
Antimicrobial Use at the End of Life
Baghban A, Juthani-Mehta M. Antimicrobial Use at the End of Life. Infectious Disease Clinics Of North America 2017, 31: 639-647. PMID: 29079153, DOI: 10.1016/j.idc.2017.07.009.Peer-Reviewed Original ResearchBurden and Management of Multidrug-Resistant Organisms in Palliative Care
Datta R, Juthani-Mehta M. Burden and Management of Multidrug-Resistant Organisms in Palliative Care. Palliative Care And Social Practice 2017, 10: 1178224217749233. PMID: 29317826, PMCID: PMC5753884, DOI: 10.1177/1178224217749233.Peer-Reviewed Original ResearchMultidrug-resistant organismsPalliative careTerminal illnessGoals of palliationPalliative care patientsPalliative care settingAvailable treatment optionsInfection prevention measuresQuality of lifeCommon complicationContact precautionsMetastatic diseaseCare patientsPatient isolationTreatment optionsSymptom assessmentCare discussionsAntimicrobial therapyCommon signsCare settingsCognitive impairmentPsychological burdenPatientsInfectionAdverse effects
2014
The Evolving Landscape of Healthcare-Associated Infections: Recent Advances in Prevention and a Road Map for Research
Safdar N, Anderson DJ, Braun BI, Carling P, Cohen S, Donskey C, Drees M, Harris A, Henderson DK, Huang SS, Juthani-Mehta M, Lautenbach E, Linkin DR, Meddings J, Miller LG, Milstone A, Morgan D, Sengupta S, Varman M, Yokoe D, Zerr DM. The Evolving Landscape of Healthcare-Associated Infections: Recent Advances in Prevention and a Road Map for Research. Infection Control And Hospital Epidemiology 2014, 35: 480-493. PMID: 24709716, PMCID: PMC4226401, DOI: 10.1086/675821.Peer-Reviewed Original Research
2013
Diagnosis and Management of Urinary Tract Infection in Older Adults
Rowe TA, Juthani-Mehta M. Diagnosis and Management of Urinary Tract Infection in Older Adults. Infectious Disease Clinics Of North America 2013, 28: 75-89. PMID: 24484576, PMCID: PMC4079031, DOI: 10.1016/j.idc.2013.10.004.Peer-Reviewed Original ResearchUrinary tract infection in older adults
Rowe TA, Juthani-Mehta M. Urinary tract infection in older adults. Aging Health 2013, 9: 519-528. PMID: 24391677, PMCID: PMC3878051, DOI: 10.2217/ahe.13.38.Peer-Reviewed Original ResearchUrinary tract infectionTract infectionsAsymptomatic bacteriuriaOlder adultsSymptomatic urinary tract infectionLong-term care facilitiesMultidrug-resistant organismsEvidence-based approachGenitourinary symptomsGold standard definitionConsensus guidelinesDiagnostic challengeCare facilitiesInfectionBacteriuriaDiagnostic accuracyYoung adultsDiagnosisAdultsCliniciansFuture studiesStandard definitionSignificant problemSymptomsPrevalence
2012
Surveillance Definitions of Infections in Long-Term Care Facilities: Revisiting the McGeer Criteria
Stone ND, Ashraf MS, Calder J, Crnich CJ, Crossley K, Drinka PJ, Gould CV, Juthani-Mehta M, Lautenbach E, Loeb M, MacCannell T, Malani PN, Mody L, Mylotte JM, Nicolle LE, Roghmann MC, Schweon SJ, Simor AE, Smith PW, Stevenson KB, Bradley SF. Surveillance Definitions of Infections in Long-Term Care Facilities: Revisiting the McGeer Criteria. Infection Control And Hospital Epidemiology 2012, 33: 965-977. PMID: 22961014, PMCID: PMC3538836, DOI: 10.1086/667743.Peer-Reviewed Original ResearchConceptsLong-term care facilitiesSurveillance definitionsCare facilitiesClostridum difficile infectionRespiratory tract infectionsExpert consensus panelMcGeer criteriaTract infectionsUrinary tractDifficile infectionConsensus panelNorovirus gastroenteritisInfectionStructured reviewSignificant changesGastroenteritisTract
2011
Adverse Outcomes in Nursing Home Residents with Increased Episodes of Observed Bacteriuria
Das R, Towle V, Ness P, Juthani-Mehta M. Adverse Outcomes in Nursing Home Residents with Increased Episodes of Observed Bacteriuria. Infection Control And Hospital Epidemiology 2011, 32: 84-86. PMID: 21091203, PMCID: PMC3089439, DOI: 10.1086/657664.Peer-Reviewed Original ResearchAdverse Outcomes in Nursing Home Residents with Increased Episodes of Observed Bacteriuria
Das R, Towle V, Ness P, Juthani-Mehta M. Adverse Outcomes in Nursing Home Residents with Increased Episodes of Observed Bacteriuria. Infection Control And Hospital Epidemiology 2011, 32: 84-86. DOI: 10.1086/657592.Peer-Reviewed Original Research
2010
Infectious Diseases in the Nursing Home Setting: Challenges and Opportunities for Clinical Investigation
High K, Juthani-Mehta M, Quagliarello V. Infectious Diseases in the Nursing Home Setting: Challenges and Opportunities for Clinical Investigation. Clinical Infectious Diseases 2010, 51: 931-936. PMID: 20822459, PMCID: PMC3083824, DOI: 10.1086/656411.Peer-Reviewed Original ResearchConceptsNursing home residentsHome residentsInfectious diseasesNursing homesNursing home settingMultiple comorbid diseasesPublic health problemComorbid diseasesHigh prevalenceFunctional declineClinical investigationPhysician investigatorsHealth problemsDiseaseHome settingOlder AmericansUnique issuesResidentsImmunosenescencePrognosisDementiaInfectionPrevalenceDiagnosis
2009
Antimicrobial Susceptibility of Bacteria Isolated from Urine Samples Obtained from Nursing Home Residents
Das R, Perrelli E, Towle V, Van Ness PH, Juthani-Mehta M. Antimicrobial Susceptibility of Bacteria Isolated from Urine Samples Obtained from Nursing Home Residents. Infection Control And Hospital Epidemiology 2009, 30: 1116-1119. PMID: 19785518, PMCID: PMC2866029, DOI: 10.1086/647981.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAnti-Bacterial AgentsDrug Resistance, BacterialEnterobacteriaceaeEnterobacteriaceae InfectionsEscherichia coliEscherichia coli InfectionsFemaleHomes for the AgedHumansMaleMicrobial Sensitivity TestsNitrofurantoinNursing HomesTrimethoprim, Sulfamethoxazole Drug CombinationUrinary Tract InfectionsUrineConceptsUrinary tract infectionNursing home residentsTract infectionsHome residentsUrine samplesEmpiric antimicrobial therapyOral antibioticsAntibiotic therapyIndwelling catheterTrimethoprim-sulfamethoxazoleAntimicrobial therapyResistance patternsAntimicrobial susceptibilityPredominant organismTherapyInfectionResidentsCatheterNitrofurantoinMeningitis in a College Student in Connecticut, 2007
Sosa LE, Gupta S, Juthani-Mehta M, Hadler JL. Meningitis in a College Student in Connecticut, 2007. Journal Of American College Health 2009, 58: 12-14. PMID: 19592348, DOI: 10.3200/jach.58.1.12-14.Peer-Reviewed Original ResearchClinical Features to Identify Urinary Tract Infection in Nursing Home Residents: A Cohort Study
Juthani‐Mehta M, Quagliarello V, Perrelli E, Towle V, Van Ness PH, Tinetti M. Clinical Features to Identify Urinary Tract Infection in Nursing Home Residents: A Cohort Study. Journal Of The American Geriatrics Society 2009, 57: 963-970. PMID: 19490243, PMCID: PMC2692075, DOI: 10.1111/j.1532-5415.2009.02227.x.Peer-Reviewed Original ResearchConceptsUrinary tract infectionNursing home residentsClinical featuresHome residentsCohort studyTract infectionsMental statusPresence of dysuriaObservational cohort studyArea nursing homesUrine culturePyuriaClinical definitionBacteriuriaHigh riskLower riskDiagnostic uncertaintyNursing homesCombined outcomeDysuriaInfectionUrineOutcomesEpisodesRisk
2008
Interobserver Variability in the Assessment of Clinical Criteria for Suspected Urinary Tract Infection in Nursing Home Residents
Juthani-Mehta M, Tinetti M, Perrelli E, Towle V, Van Ness PH, Quagliarello V. Interobserver Variability in the Assessment of Clinical Criteria for Suspected Urinary Tract Infection in Nursing Home Residents. Infection Control And Hospital Epidemiology 2008, 29: 446-449. PMID: 18419369, PMCID: PMC2671070, DOI: 10.1086/586721.Peer-Reviewed Original Research
2007
Asymptomatic Bacteriuria and Urinary Tract Infection in Older Adults
Juthani-Mehta M. Asymptomatic Bacteriuria and Urinary Tract Infection in Older Adults. Clinics In Geriatric Medicine 2007, 23: 585-594. PMID: 17631235, DOI: 10.1016/j.cger.2007.03.001.Peer-Reviewed Original ResearchRole of Dipstick Testing in the Evaluation of Urinary Tract Infection in Nursing Home Residents
Juthani-Mehta M, Tinetti M, Perrelli E, Towle V, Quagliarello V. Role of Dipstick Testing in the Evaluation of Urinary Tract Infection in Nursing Home Residents. Infection Control And Hospital Epidemiology 2007, 28: 889-891. PMID: 17564998, DOI: 10.1086/518752.Peer-Reviewed Original ResearchDiagnostic Accuracy of Criteria for Urinary Tract Infection in a Cohort of Nursing Home Residents*
Juthani‐Mehta M, Tinetti M, Perrelli E, Towle V, Van Ness PH, Quagliarello V. Diagnostic Accuracy of Criteria for Urinary Tract Infection in a Cohort of Nursing Home Residents*. Journal Of The American Geriatrics Society 2007, 55: 1072-1077. PMID: 17608881, DOI: 10.1111/j.1532-5415.2007.01217.x.Peer-Reviewed Original ResearchConceptsUrinary tract infectionNursing home residentsNegative predictive valuePositive predictive valueConsensus-based criteriaLaboratory evidenceHome residentsTract infectionsPredictive valueEvidence-based clinical criteriaDiagnostic accuracyProspective cohort studySimilar test characteristicsMcGeer criteriaUTI criteriaCohort studyProspective surveillanceUrine cultureClinical criteriaNursing homesTest characteristicsInfectionLoeb criteriaParticipantsSpecificity