Juxtacrine cell signaling molecules
Bosenberg M, Massagué J. Juxtacrine cell signaling molecules. Current Opinion In Cell Biology 1993, 5: 832-838. PMID: 7694603, DOI: 10.1016/0955-0674(93)90032-l.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell AdhesionCell Adhesion MoleculesCell MembraneDrosophila ProteinsEpidermal Growth FactorEye ProteinsGrowth SubstancesHematopoietic Cell Growth FactorsHumansMembrane GlycoproteinsNerve Growth FactorsReceptors, Cell SurfaceReceptors, PeptideSignal TransductionStem Cell FactorTumor Necrosis Factor-alphaConceptsCell adhesion moleculeMembrane-anchored growth factorsIntimate cell-cell contactCell-cell contactDiffusible growth factorsAdhesion moleculesGrowth factorTissue developmentIntercellular communicationJuxtacrine interactionsJuxtacrine stimulationClass of moleculesAdjacent cellsCellsRapid progressMoleculesReceptorsBiologistsMaintenanceIdentificationActivated release of membrane-anchored TGF-alpha in the absence of cytosol
Bosenberg M, Pandiella A, Massagué J. Activated release of membrane-anchored TGF-alpha in the absence of cytosol. Journal Of Cell Biology 1993, 122: 95-101. PMID: 8314849, PMCID: PMC2119606, DOI: 10.1083/jcb.122.1.95.Peer-Reviewed Original ResearchMeSH KeywordsAluminumAluminum CompoundsAnimalsCell MembraneCell Membrane PermeabilityCHO CellsCricetinaeFluoridesFluorineGTP-Binding ProteinsGuanosine 5'-O-(3-Thiotriphosphate)Guanosine DiphosphateKineticsProtein Kinase CProtein PrecursorsProtein Processing, Post-TranslationalRatsRecombinant ProteinsTetradecanoylphorbol AcetateThionucleotidesTransfectionTransforming Growth Factor alphaConceptsMembrane-anchored growth factorsHeterotrimeric G proteinsCell surfaceIndependent protein kinase CCellular proteolytic systemsStreptolysin OProtein kinase CAbsence of cytosolVesicular trafficCytoplasmic tailATP hydrolysisProteolytic componentKinase CG proteinsProteolytic systemIntact cellsPermeabilized cellsGTP gamma SBiochemical componentsCytosolAlpha cleavageTGF-alphaRegulated systemGamma SGrowth factor