2001
SP-RING for SUMO New Functions Bloom for a Ubiquitin-like Protein
Hochstrasser M. SP-RING for SUMO New Functions Bloom for a Ubiquitin-like Protein. Cell 2001, 107: 5-8. PMID: 11595179, DOI: 10.1016/s0092-8674(01)00519-0.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid MotifsAnimalsFungal ProteinsGTPase-Activating ProteinsHumansLigasesProtein BindingProtein Processing, Post-TranslationalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSUMO-1 ProteinUbiquitin-Protein Ligases
1998
There’s the Rub: a novel ubiquitin-like modification linked to cell cycle regulation
Hochstrasser M. There’s the Rub: a novel ubiquitin-like modification linked to cell cycle regulation. Genes & Development 1998, 12: 901-907. PMID: 9531529, DOI: 10.1101/gad.12.7.901.Peer-Reviewed Original Research
1996
Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly
Chen P, Hochstrasser M. Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly. Cell 1996, 86: 961-972. PMID: 8808631, DOI: 10.1016/s0092-8674(00)80171-3.Peer-Reviewed Original ResearchProtein Degradation or Regulation: Ub the Judge
Hochstrasser M. Protein Degradation or Regulation: Ub the Judge. Cell 1996, 84: 813-815. PMID: 8601303, DOI: 10.1016/s0092-8674(00)81058-2.Peer-Reviewed Original Research
1990
In vivo degradation of a transcriptional regulator: The yeast α2 repressor
Hochstrasser M, Varshavsky A. In vivo degradation of a transcriptional regulator: The yeast α2 repressor. Cell 1990, 61: 697-708. PMID: 2111732, DOI: 10.1016/0092-8674(90)90481-s.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBeta-GalactosidaseFungal ProteinsGene Expression Regulation, FungalHalf-LifeMacromolecular SubstancesMolecular Sequence DataMutationProtein EngineeringProtein Processing, Post-TranslationalRecombinant Fusion ProteinsRepressor ProteinsSaccharomyces cerevisiaeTranscription FactorsConceptsYeast S. cerevisiaeTranscriptional regulatorsHeteromeric proteinsAlpha 2S. cerevisiaeDegradation signalRegulatory proteinsOligomeric proteinsSame proteinStructural domainsProteinMultiple functionsSubunitsRepressorDistinct mechanismsVivo concentrationsAdditional defectsCerevisiaeMutantsNovel typeDegradationRegulatorPathwayMetabolic instabilityVivo degradation