2009
Auto‐inhibition of dynamin GTPase activity is regulated by PH domain interactions
Kenniston J, Lemmon M. Auto‐inhibition of dynamin GTPase activity is regulated by PH domain interactions. The FASEB Journal 2009, 23: 697.3-697.3. DOI: 10.1096/fasebj.23.1_supplement.697.3.Peer-Reviewed Original ResearchGTPase activityDynamin pleckstrin homology domainDynamin GTPase activityPleckstrin homology domainGTP hydrolysis ratePH domain interactionJane Coffin Childs Memorial FundReceptor-mediated endocytosisGTPase domainHomology domainDynamin GTPaseInteraction motifsGTP hydrolysisAbsence of lipidsConformational interplaySelective mutagenesisDomain interactionsGTPase rateVesicle interactionsDynaminScission eventsDistinct groupsGTPaseMutagenesisEndocytosis
2003
Genome-wide analysis of signaling domain function
Yu JW, Lemmon MA. Genome-wide analysis of signaling domain function. Current Opinion In Chemical Biology 2003, 7: 103-109. PMID: 12547434, DOI: 10.1016/s1367-5931(02)00008-x.Peer-Reviewed Original Research
2001
The Single Transmembrane Domains of ErbB Receptors Self-associate in Cell Membranes*
Mendrola JM, Berger MB, King MC, Lemmon MA. The Single Transmembrane Domains of ErbB Receptors Self-associate in Cell Membranes*. Journal Of Biological Chemistry 2001, 277: 4704-4712. PMID: 11741943, DOI: 10.1074/jbc.m108681200.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid MotifsAmino Acid SequenceCell MembraneChloramphenicol O-AcetyltransferaseDimerizationDNA Mutational AnalysisErbB ReceptorsEscherichia coliGenetic VectorsGlutamic AcidHumansLigandsMaltoseModels, MolecularMolecular Sequence DataMutagenesis, Site-DirectedMutationProtein Structure, TertiaryReceptor Protein-Tyrosine KinasesReceptor, ErbB-2Receptor, ErbB-3Receptor, ErbB-4Recombinant Fusion ProteinsSequence Homology, Amino AcidValineConceptsTM domain interactionsTM domainReceptor tyrosine kinasesEpidermal growth factor receptorGrowth factor receptorDomain interactionsSingle transmembrane alpha-helixReceptor dimersTyrosine kinaseExtracellular domainErbB receptor functionEscherichia coli cell membraneSingle transmembrane domainTransmembrane alpha-helixErbB receptorsCell membraneLimited mutational analysisFactor receptorGlutamic acid mutationTransmembrane domainGxxxG motifDomain dimerMutational analysisAlpha-helixErythropoietin receptor