2001
Post-translational protein modifications in antigen recognition and autoimmunity
Doyle H, Mamula M. Post-translational protein modifications in antigen recognition and autoimmunity. Trends In Immunology 2001, 22: 443-449. PMID: 11473834, DOI: 10.1016/s1471-4906(01)01976-7.Peer-Reviewed Original Research
1996
B7 costimulation and autoantigen specificity enable B cells to activate autoreactive T cells.
Roth R, Nakamura T, Mamula M. B7 costimulation and autoantigen specificity enable B cells to activate autoreactive T cells. The Journal Of Immunology 1996, 157: 2924-31. PMID: 8816398, DOI: 10.4049/jimmunol.157.7.2924.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsAntibodies, MonoclonalAntigen PresentationAntigens, CDAutoantigensAutoimmunityB7-1 AntigenB7-2 AntigenBase SequenceB-LymphocytesCell MovementCytochrome c GroupCytokinesFemaleGene Expression RegulationImmunizationLymph NodesLymphocyte ActivationMembrane GlycoproteinsMiceMolecular Sequence DataPeptide FragmentsPolymerase Chain ReactionRatsRNA, MessengerSelf ToleranceSignal TransductionT-Lymphocyte SubsetsConceptsAutoreactive T cellsT cell responsesT cellsB cellsIL-4IL-5Self-AgImmunized B-cell-deficient miceCell responsesAutoimmune T cell responsesB cell-deficient miceB7-1 costimulatory moleculeT cell autoimmunityCell-deficient miceTreatment of miceT cell toleranceNaive T cellsCytokine mRNA responsesCell autoimmunityB7 costimulationCostimulatory moleculesAutoantigen specificityB7-2Cytokine mRNAIFN-gamma
1992
Breaking T cell tolerance with foreign and self co-immunogens. A study of autoimmune B and T cell epitopes of cytochrome c.
Mamula M, Lin R, Janeway C, Hardin J. Breaking T cell tolerance with foreign and self co-immunogens. A study of autoimmune B and T cell epitopes of cytochrome c. The Journal Of Immunology 1992, 149: 789-95. PMID: 1321851, DOI: 10.4049/jimmunol.149.3.789.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAutoantigensAutoimmunityB-LymphocytesCross ReactionsCytochrome c GroupGene Rearrangement, beta-Chain T-Cell Antigen ReceptorHumansImmune ToleranceLymphocyte ActivationMiceMice, Inbred StrainsRatsReceptors, Antigen, T-Cell, alpha-betaSequence AlignmentSpecies SpecificityT-LymphocytesConceptsT cell responsesT cell toleranceB cellsCell responsesCell toleranceSelf-AgAutoimmune T cell responsesAutoreactive T cell responsesAutoreactive T cell clonesTCR genesAutoimmune B cellsCellular immune responsesImmune B cellsAutoreactive B cellsT cell clonesT cell epitopesAmino acids 54Autoimmune diseasesT cellsImmune responseCell epitopesForeign pathogensModel autoantigenImmunizationCell clones