Obesity Accelerates T-Cell Leukemia in a Spontaneous Mouse Model.
Yun J, Klemm L, Behan J, Müschen M, Mittelman S. Obesity Accelerates T-Cell Leukemia in a Spontaneous Mouse Model. Blood 2008, 112: 1909. DOI: 10.1182/blood.v112.11.1909.1909.Peer-Reviewed Original ResearchAKR/J miceSpontaneous T cell leukemiaT-cell leukemiaT cell maturationDiet-induced obesityJ miceOnset of leukemiaLeukemic miceDiet groupMouse modelControl dietEffect of obesityCD4/CD8Non-obese counterpartsT cell subgroupsHigh-fat dietSpontaneous mouse modelMonths of ageT cell differentiationWeeks of ageTypes of cancerCD4/ CD8Clinical illnessThymus weightLifestyle parameters