2004
A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation Potential
Kögler G, Sensken S, Airey JA, Trapp T, Müschen M, Feldhahn N, Liedtke S, Sorg R, Fischer J, Rosenbaum C, Greschat S, Knipper A, Bender J, Degistirici O, Gao J, Caplan AI, Colletti EJ, Almeida-Porada G, Müller H, Zanjani E, Wernet P. A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation Potential. Journal Of Experimental Medicine 2004, 200: 123-135. PMID: 15263023, PMCID: PMC2212008, DOI: 10.1084/jem.20040440.Peer-Reviewed Original ResearchMeSH KeywordsAdipocytesAlbuminsAnimalsBlotting, WesternBone and BonesCell Culture TechniquesCell DifferentiationCell DivisionCell LineCell TransplantationCord Blood Stem Cell TransplantationFemurFetal BloodFlow CytometryGene Expression Regulation, DevelopmentalHematopoietic Stem CellsHippocampusHumansImmunophenotypingLeukocyte Common AntigensLeukocytes, MononuclearMyocardiumMyocytes, CardiacNeurotransmitter AgentsOsteoblastsPhenotypePlacentaPolymerase Chain ReactionRatsRats, WistarReverse Transcriptase Polymerase Chain ReactionSheepStem CellsTime FactorsUmbilical VeinsConceptsUnrestricted somatic stem cellsSomatic stem cellsHuman somatic stem cellsStem cellsPluripotent differentiation potentialSodium channel proteinEndodermal pathwayHuman cord bloodUSSC transplantationCord bloodChannel proteinsNeuron-like morphologyHomogeneous differentiationCell fusionIntact adult rat brainDifferentiation potentialRare populationParenchymal hepatic cellsTau-positive cellsVivo differentiationNeural cellsTumor formationPlacental cord bloodPreimmune fetal sheepAdult rat brain
2001
Molecular Single-Cell Analysis of Hodgkin- and Reed-Sternberg Cells Harboring Unmutated Immunoglobulin Variable Region Genes
Müschen M, Küppers R, Spieker T, Bräuninger A, Rajewsky K, Hansmann M. Molecular Single-Cell Analysis of Hodgkin- and Reed-Sternberg Cells Harboring Unmutated Immunoglobulin Variable Region Genes. Laboratory Investigation 2001, 81: 289-295. PMID: 11310822, DOI: 10.1038/labinvest.3780237.Peer-Reviewed Original ResearchConceptsImmunoglobulin variable region genesRegion genesVariable region genesGerminal center B cellsSomatic mutationsFounder cellsGerminal center founder cellsB cellsGenesIntrinsic propensityClonal progenyUnmutated immunoglobulin variable region genesClassical Hodgkin's diseaseAntigen-experienced B cellsCell analysisRS cellsMutationsNaive B cellsReed-Sternberg cellsCellsB-lineageLineagesProgenyClonesApoptosis