2012
p21-Activated kinase 4 promotes prostate cancer progression through CREB
Park M, Lee H, Lee C, You S, Kim D, Park B, Kang M, Heo W, Shin E, Schwartz M, Kim E. p21-Activated kinase 4 promotes prostate cancer progression through CREB. Oncogene 2012, 32: 2475-2482. PMID: 22710715, DOI: 10.1038/onc.2012.255.Peer-Reviewed Original ResearchConceptsP21-activated kinase 4Prostate cancer progressionProstate cancerCancer progressionLNCaP-FGC cellsPromising therapeutic targetKinase 4Prostate cancer cellsDU145 prostate cancer cellsSpecific protein kinase A (PKA) inhibitorProtein kinase A (PKA) inhibitorElevation of cAMPNeuroendocrine differentiationNude miceTherapeutic targetActive PAK4Downstream effector pathwaysTumor progressionDecreased expressionTumor formationCancerCancer cellsPC-3ProgressionEffector pathways
1989
Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts.
Schwartz M, Both G, Lechene C. Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 4525-4529. PMID: 2734302, PMCID: PMC287303, DOI: 10.1073/pnas.86.12.4525.Peer-Reviewed Original Research