Depression, Inflammation, and Intestinal Permeability: Associations with Subjective and Objective Cognitive Functioning throughout Breast Cancer Survivorship
Madison A, Andridge R, Kantaras A, Renna M, Bennett J, Alfano C, Povoski S, Agnese D, Lustberg M, Wesolowski R, Carson W, Williams N, Reinbolt R, Sardesai S, Noonan A, Stover D, Cherian M, Malarkey W, Kiecolt-Glaser J. Depression, Inflammation, and Intestinal Permeability: Associations with Subjective and Objective Cognitive Functioning throughout Breast Cancer Survivorship. Cancers 2023, 15: 4414. PMID: 37686689, PMCID: PMC10487080, DOI: 10.3390/cancers15174414.Peer-Reviewed Original ResearchBreast cancer survivorsSignificant depressive symptomsIntestinal permeabilityCancer survivorsDepressive symptomsObjective cognitive functionCognitive functionStudy visitCognitive declineEpidemiological Studies Depression ScaleCancer treatment typeInflammation-associated depressionC-reactive proteinCancer Survivor StudyBreast cancer survivorshipTumor necrosis factorCognitive function testsLipopolysaccharide binding proteinHopkins Verbal Learning TestSubjective cognitive functionObjective cognitive impairmentLower verbal fluencyInflammatory indexInflammatory markersElevated inflammationA troubled heart: Mood disorder history longitudinally predicts faster cardiopulmonary aging in breast cancer survivorship
Madison A, Filatov M, Andridge R, Haas G, Povoski S, Agnese D, Lustberg M, Reinbolt R, Wesolowski R, Williams N, Malarkey W, Kiecolt-Glaser J. A troubled heart: Mood disorder history longitudinally predicts faster cardiopulmonary aging in breast cancer survivorship. PLOS ONE 2023, 18: e0283849. PMID: 37000800, PMCID: PMC10065250, DOI: 10.1371/journal.pone.0283849.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsMood disorder historyExercise stress testCancer survivorsCardiovascular diseaseDisorder historyDepressive symptomsTreatment typeEpidemiologic Studies Depression ScaleNon-cancer causesBreast cancer survivorshipStructured Clinical InterviewAdvanced cancer treatmentStress testCardiotoxic treatmentsAdjuvant treatmentCross-sectional relationshipAntidepressant useTrunk fatCVD developmentVisit 1Depression ScaleCancer survivorshipPhysical activityClinical Interview