2012
Multiparameter Analysis, including EMT Markers, on Negatively Enriched Blood Samples from Patients with Squamous Cell Carcinoma of the Head and Neck
Balasubramanian P, Lang J, Jatana K, Miller B, Ozer E, Old M, Schuller D, Agrawal A, Teknos T, Summers T, Lustberg M, Zborowski M, Chalmers J. Multiparameter Analysis, including EMT Markers, on Negatively Enriched Blood Samples from Patients with Squamous Cell Carcinoma of the Head and Neck. PLOS ONE 2012, 7: e42048. PMID: 22844540, PMCID: PMC3406036, DOI: 10.1371/journal.pone.0042048.Peer-Reviewed Original ResearchConceptsEpithelial surface markersN-cadherinEpidermal growth factor receptorGrowth factor receptorSurface markersPositive selection approachEpithelial markersAforementioned proteinsMesenchymal transitionFactor receptorConfocal microscopyCancer metastasisEMT processCancer cellsPhenotypic patternsMesenchymal markersTumor metastasisEnrichment methodologyEMT markersEnrichment technologyCellsEMTExpressionTumor cellsMarkers
2009
Epigenetic targeting in breast cancer: therapeutic impact and future direction.
Lustberg M, Ramaswamy B. Epigenetic targeting in breast cancer: therapeutic impact and future direction. Drug News & Perspectives 2009, 22: 369-81. PMID: 19890494, PMCID: PMC3658161, DOI: 10.1358/dnp.2009.22.7.1405072.Peer-Reviewed Original ResearchConceptsEpigenetic changesHistone modificationsHistone deacetylase inhibitorsGene expressionMajor epigenetic changesHeritable changesRepressor complexDNA methylationGene sequencesEpigenetic targetingDeacetylase inhibitorsMultistep processMethylationExpressionEpigeneticsBreast carcinogenesisGenesReversible processAntiapoptosisNovel therapiesSequenceInvasionProliferationTargetingBreast cancer