2017
Phase Ib study of heat shock protein 90 inhibitor, onalespib in combination with paclitaxel in patients with advanced, triple-negative breast cancer (NCT02474173).
Wesolowski R, Lustberg M, Reinbolt R, VanDeusen J, Sardesai S, Williams N, Noonan A, Dewani S, Poi M, Wilson D, Grever M, Stephens J, Puhalla S, Mathew A, Carson W, Ramaswamy B. Phase Ib study of heat shock protein 90 inhibitor, onalespib in combination with paclitaxel in patients with advanced, triple-negative breast cancer (NCT02474173). Journal Of Clinical Oncology 2017, 35: tps1127-tps1127. DOI: 10.1200/jco.2017.35.15_suppl.tps1127.Peer-Reviewed Original ResearchTriple-negative breast cancerBreast cancerDay 1Hormone receptor-positive breast cancerReceptor-positive breast cancerPhase Ib studyPhase II doseProgression-free survivalPositive breast cancerOverall response rateHeat shock protein 90 inhibitorNegative breast cancerCycle 1Shock protein 90 inhibitorsPoor outcomeStandard doseAndrogen receptorHsp90 client proteinsHeat shock protein 90Ib studyResponse durationToxicity profilePaclitaxel resistanceClient proteinsDay 7
2016
Breast cancer and social environment: getting by with a little help from our friends
Hinzey A, Gaudier-Diaz M, Lustberg M, DeVries A. Breast cancer and social environment: getting by with a little help from our friends. Breast Cancer Research 2016, 18: 54. PMID: 27225892, PMCID: PMC4881170, DOI: 10.1186/s13058-016-0700-x.Peer-Reviewed Original ResearchConceptsTumor growthBreast cancerBreast cancer survivorsBreast cancer patientsIdentification of patientsCancer-related mortalityMammary tumor growthBreast cancer progressionBasic science literatureInadequate social supportTherapeutic complementCancer survivorsPoor outcomeCancer patientsTumor progressionProtective pathwaysContemporary treatmentDetrimental pathwaysCancer progressionTargeted disruptionUnderlying physiological mechanismsSocial isolationPatientsCancerSocial support
2015
Effects of chemotherapy on quality of life in breast cancer survivors.
Wandell K, Lustberg M, Reinbolt R, Orchard T, Andridge R, Wandell H, Schade C, Moran T, Yang N, Conlan T. Effects of chemotherapy on quality of life in breast cancer survivors. Journal Of Clinical Oncology 2015, 33: 112-112. DOI: 10.1200/jco.2015.33.28_suppl.112.Peer-Reviewed Original ResearchBody mass indexDuke Activity Status IndexQuality of lifeInitiation of treatmentBreast cancer survivorsNutrition-related symptomsFunctional statusCancer survivorsFunctional capacityFirst cycle chemotherapyPG-SGA scoreSubjective Global AssessmentPatients' functional statusDuration of chemotherapyEffect of chemotherapyPeak oxygen uptakeCycle chemotherapyPG-SGAAdjuvant therapySymptom burdenMedian ageMass indexPoor outcomeSignificant changesBreast cancer