2010
Inhibition of the c-fms proto-oncogene autocrine loop and tumor phenotype in glucocorticoid stimulated human breast carcinoma cells
Toy EP, Lamb T, Azodi M, Roy WJ, Woo HH, Chambers SK. Inhibition of the c-fms proto-oncogene autocrine loop and tumor phenotype in glucocorticoid stimulated human breast carcinoma cells. Breast Cancer Research And Treatment 2010, 129: 411-419. PMID: 21063905, DOI: 10.1007/s10549-010-1247-7.Peer-Reviewed Original ResearchMeSH KeywordsAutocrine CommunicationBreast NeoplasmsCarcinomaCell AdhesionCell Line, TumorCell MovementDexamethasoneDose-Response Relationship, DrugFemaleGlucocorticoidsHumansMacrophage Colony-Stimulating FactorNeoplasm InvasivenessOligonucleotides, AntisensePhenotypePhenylurea CompoundsProtein Kinase InhibitorsProto-Oncogene MasReceptor, Macrophage Colony-Stimulating FactorRNA InterferenceThiazolesTransfectionConceptsC-fms signalingBreast cancer cellsAntisense oligonucleotide therapyBreast cancerGC stimulationC-fms expressionCancer cellsBreast cancer cell invasionTargeted molecular therapiesHuman breast cancer cellsCo-expressed receptorsAutocrine feedback loopDose-response mannerC-fms mRNAHuman breast carcinoma cellsBreast tumor behaviorReceptor/ligand pairsBreast carcinoma cellsCancer cell invasionInhibition of glucocorticoidsC-fmsAutocrine pathwayClinical utilityParacrine mannerTumor behavior
2009
Enhanced Ovarian Cancer Tumorigenesis and Metastasis by the Macrophage Colony-Stimulating Factor
Toy EP, Azodi M, Folk NL, Zito CM, Zeiss CJ, Chambers SK. Enhanced Ovarian Cancer Tumorigenesis and Metastasis by the Macrophage Colony-Stimulating Factor. Neoplasia 2009, 11: 136-144. PMID: 19177198, PMCID: PMC2631138, DOI: 10.1593/neo.81150.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkers, TumorCell AdhesionCell MovementCell Transformation, NeoplasticFemaleHumansMacrophage Colony-Stimulating FactorMiceMice, NudeNeoplasm InvasivenessNeoplasm MetastasisNeoplasm TransplantationNeoplasms, ExperimentalOligonucleotides, AntisenseOvarian NeoplasmsPhenotypeReceptor, Macrophage Colony-Stimulating FactorTumor Cells, Cultured