2024
Underuse of Postoperative Radiation After Nipple-Sparing Mastectomy for Standard Radiation Indications
Talcott W, Marta G, Moran M. Underuse of Postoperative Radiation After Nipple-Sparing Mastectomy for Standard Radiation Indications. Advances In Radiation Oncology 2024, 9: 101569. PMID: 39188995, PMCID: PMC11345291, DOI: 10.1016/j.adro.2024.101569.Peer-Reviewed Original ResearchPost-operative radiationNipple-sparing mastectomyRegional nodal irradiationAdverse pathologic featuresOverall survivalPathological featuresEarly-stage breast cancerNational Cancer DatabasePost-operative settingType of surgeryHigh-risk subgroupsNipple preservationNodal irradiationPN+ ratePositive marginsRadiation deliveryInvasive carcinomaSurgical subtypesCancer DatabaseLymph nodesPatient selectionPN+Breast cancerCox regressionMultivariate analysis
2016
Society of Surgical Oncology–American Society for Radiation Oncology–American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ
Morrow M, Van Zee KJ, Solin LJ, Houssami N, Chavez-MacGregor M, Harris JR, Horton J, Hwang S, Johnson PL, Marinovich ML, Schnitt SJ, Wapnir I, Moran MS. Society of Surgical Oncology–American Society for Radiation Oncology–American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ. Journal Of Clinical Oncology 2016, 34: 4040-4046. PMID: 27528719, PMCID: PMC5477830, DOI: 10.1200/jco.2016.68.3573.Peer-Reviewed Original ResearchConceptsIpsilateral breast tumor recurrenceWhole breast irradiationRisk of IBTRNegative marginsDuctal carcinomaRate of IBTRSurgical Oncology–American SocietyMargin widthMultidisciplinary consensus panelBreast tumor recurrenceBreast conserving surgeryBreast-conserving surgeryNegative margin widthOptimal negative margin widthRe-excision ratesHealth care costsFurther surgeryPositive marginsBreast irradiationConsensus guidelinesCosmetic outcomeTumor recurrenceClear marginsConsensus panelBackground Controversy
2014
Nomogram for Predicting the Risk of Locoregional Recurrence in Patients Treated With Accelerated Partial-Breast Irradiation
Wobb JL, Chen PY, Shah C, Moran MS, Shaitelman SF, Vicini FA, Mbah AK, Lyden M, Beitsch P. Nomogram for Predicting the Risk of Locoregional Recurrence in Patients Treated With Accelerated Partial-Breast Irradiation. International Journal Of Radiation Oncology • Biology • Physics 2014, 91: 312-318. PMID: 25446607, DOI: 10.1016/j.ijrobp.2014.09.029.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAlgorithmsBrachytherapyBreast NeoplasmsDose Fractionation, RadiationFemaleHumansMiddle AgedNeoplasm Recurrence, LocalNomogramsOrgan Sparing TreatmentsOutcome Assessment, Health CarePrognosisReproducibility of ResultsRisk AssessmentSensitivity and SpecificityUnited StatesConceptsLocoregional recurrencePartial breast irradiationConcordance indexBreast Surgeons MammoSite Registry TrialCox proportional hazards regression modelRisk of LRREarly-stage breast cancerProportional hazards regression modelsAccelerated Partial Breast IrradiationEstrogen receptor negativityBalloon-based brachytherapyHazards regression modelsWilliam Beaumont HospitalConformal radiation therapyBias-corrected indicesReceptor negativityRegistry trialClinicopathologic featuresPositive marginsClinicopathologic variablesBeaumont HospitalUnivariate analysisBreast cancerUse nomogramRadiation therapyNomogram for predicting the risk of locoregional recurrence in patients treated with accelerated partial-breast irradiation.
Wobb J, Chen P, Shah C, Moran M, Shaitelman S, Vicini F, Mbah A, Lyden M, Beitsch P. Nomogram for predicting the risk of locoregional recurrence in patients treated with accelerated partial-breast irradiation. Journal Of Clinical Oncology 2014, 32: 59-59. DOI: 10.1200/jco.2014.32.26_suppl.59.Peer-Reviewed Original ResearchLocoregional recurrenceC-indexCox proportional hazards regression modelRisk of LRREarly-stage breast cancerProportional hazards regression modelsStage breast cancerBalloon-based brachytherapyHazards regression modelsWilliam Beaumont HospitalPartial breast irradiationBias-corrected indicesRegistry trialClinicopathologic featuresER negativityPositive marginsClinicopathologic variablesBeaumont HospitalPerimenopausal statusUnivariate analysisBreast cancerUse nomogramConformal radiotherapyPatientsAPBI