2018
Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
Stewart R, King M, Horsley V. Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease. Stem Cell Biology And Regenerative Medicine 2018, 263-292. DOI: 10.1007/978-3-319-16769-5_11.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNuclear laminaIntegral inner nuclear membrane proteinsInner nuclear membrane proteinSkin developmentMechanical signalsNuclear membrane proteinsInner nuclear membraneIntegration of biochemicalGenome integrityNuclear peripheryTranscriptional outputNuclear laminsAssociated chromatinMembrane proteinsNuclear interiorTissue-level mechanicsGene expressionNuclear membraneSkin homeostasisKeratinocyte differentiationMechanical inputChromatinLaminsLaminaProtein
2006
Karyopherin-mediated import of integral inner nuclear membrane proteins
King MC, Lusk C, Blobel G. Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 2006, 442: 1003-1007. PMID: 16929305, DOI: 10.1038/nature05075.Peer-Reviewed Original ResearchConceptsIntegral membrane proteinsInner nuclear membraneINM proteinsMembrane proteinsIntegral inner nuclear membrane proteinsInner nuclear membrane proteinNuclear pore complex proteinsNuclear membrane proteinsRan GTPase cycleBasic sequence motifsNuclear localization signalNuclear pore complexPore complex proteinsAppropriate cellular compartmentDiscrete sequence elementsINM targetingLocalization signalPore complexGTPase cycleNuclear transportSequence motifsCellular compartmentsComplex proteinsSequence elementsKaryopherin β1