2022
Catechol-O-Methyltransferase Effects on Smoking: a Review and Proof of Concept of Sex-Sensitive Effects
DeVito E, Sofuoglu M. Catechol-O-Methyltransferase Effects on Smoking: a Review and Proof of Concept of Sex-Sensitive Effects. Current Behavioral Neuroscience Reports 2022, 9: 113-123. PMID: 36644316, PMCID: PMC9838826, DOI: 10.1007/s40473-022-00251-2.Peer-Reviewed Original ResearchSmoking behaviorPreliminary dataHuman laboratory studiesCigarette smoking behaviorShort-term abstinenceNicotine administrationSmoking cessationTreatment optionsWithdrawal symptomsCessation outcomesPharmacogenetic effectsOvernight abstinenceMet carriersSmoking urgesActivity genotypeReviewThis articleSymptomsCOMT geneSex differencesAbstinenceFunctional variantsSmokingCigarettesAdministrationIndividuals
2017
Rates and correlates of specialized pain clinic use nationally in the veterans health administration
Arout C, Sofuoglu M, Rosenheck R. Rates and correlates of specialized pain clinic use nationally in the veterans health administration. Drug And Alcohol Dependence 2017, 171: e10-e11. DOI: 10.1016/j.drugalcdep.2016.08.044.Peer-Reviewed Original Research
1993
7-Benzylidenenaltrexone (BNTX): A selective δ1 opioid receptor antagonist in the mouse spinal cord
Sofuoglu M, Portoghese P, Takemori A. 7-Benzylidenenaltrexone (BNTX): A selective δ1 opioid receptor antagonist in the mouse spinal cord. Life Sciences 1993, 52: 769-775. PMID: 8383271, DOI: 10.1016/0024-3205(93)90240-4.Peer-Reviewed Original ResearchConceptsAntinociceptive ED50 valueDELT IIED50 valuesDelta opioid receptor subtypesOpioid receptor subtypesDelta-opioid receptorsSubtype-selective agonistsAntinociceptive ED50Spinal sitesOpioid receptorsReceptor subtypesSelective agonistBNTXDPDPEMiceAdministrationHand administrationAntinociceptionRecent reportsDAMGONaltribenMorphineAgonistsAntagonistED50
1991
Cross-tolerance studies in the spinal cord of β-FNA-treated mice provides further evidence for delta opioid receptor subtypes
Sofuoglu M, Portoghese P, Takemori A. Cross-tolerance studies in the spinal cord of β-FNA-treated mice provides further evidence for delta opioid receptor subtypes. Life Sciences 1991, 49: pl153-pl156. PMID: 1658509, DOI: 10.1016/0024-3205(91)90397-t.Peer-Reviewed Original ResearchConceptsDelta opioid receptor subtypesOpioid receptor subtypesAntinociceptive effectReceptor subtypesAntinociceptive ED50 valueDelta-opioid receptor-selective peptideCross-tolerance studiesReceptor-selective peptideSpinal cordTolerance developmentFurther evidenceDPDPEED50 valuesMiceDADLEDAMGOSignificant increaseDSLETSame pretreatmentSubtypesAdministrationSelective peptidesCordFNA