2001
Depressive symptoms modulate the subjective and physiological response to cocaine in humans
Sofuoglu M, Brown S, Babb D, Hatsukami D. Depressive symptoms modulate the subjective and physiological response to cocaine in humans. Drug And Alcohol Dependence 2001, 63: 131-137. PMID: 11376917, DOI: 10.1016/s0376-8716(00)00199-x.Peer-Reviewed Original ResearchConceptsDepressive symptomsCocaine responseBeck Depression Inventory scoresHigher BDI groupLower BDI scoresDepression Inventory scoresSubclinical depressive symptomsBody weight differencesInpatient studyMajor depressionBDI scoresCocaine use behaviorBDI groupInventory scoresSymptomsCocaineCocaine usersPhysiological responsesGroup differencesEnhanced responseSubjective responsesWeight differencesScoresUse behaviorsResponse
2000
Carvedilol affects the physiological and behavioral response to smoked cocaine in humans
Sofuoglu M, Brown S, Babb D, Pentel P, Hatsukami D. Carvedilol affects the physiological and behavioral response to smoked cocaine in humans. Drug And Alcohol Dependence 2000, 60: 69-76. PMID: 10821991, DOI: 10.1016/s0376-8716(00)80009-5.Peer-Reviewed Original ResearchConceptsAcute treatmentPlacebo-controlled outpatient studyPhysiological effectsEffects of carvedilolDiastolic blood pressureCocaine-induced increasesNumber of cocaineCarvedilol treatmentBlood pressureOral carvedilolOutpatient studyNoradrenergic systemAdrenergic blockersCrack cocaine usersHeart rateCarvedilolBehavioral responsesCocaineCocaine usersCocaine deliveryTreatmentSubjective responsesTreatment conditionsResponseHumans