2018
The Cholinergic System as a Treatment Target for Opioid Use Disorder
Jensen KP, DeVito EE, Yip S, Carroll KM, Sofuoglu M. The Cholinergic System as a Treatment Target for Opioid Use Disorder. CNS Drugs 2018, 32: 981-996. PMID: 30259415, PMCID: PMC6314885, DOI: 10.1007/s40263-018-0572-y.Peer-Reviewed Original ResearchConceptsCholinergic systemUse disordersTreatment targetsOpioid use disorder epidemicCentral nervous system functionTreatment of OUDEffects of acetylcholineOpioid use disorderTobacco use disorderNervous system functionOpioid medicationsDegrade acetylcholineCurrent treatmentOpioid overdosesPreclinical studiesMedicationsAcetylcholineCholinesterase inhibitorsAlzheimer's diseaseNew treatmentsAccidental deathGlobal healthTreatmentOUDDisease
2017
Neurocognitive Function as a Treatment Target for Tobacco Use Disorder
Robinson C, Waters A, Kang N, Sofuoglu M. Neurocognitive Function as a Treatment Target for Tobacco Use Disorder. Current Behavioral Neuroscience Reports 2017, 4: 10-20. DOI: 10.1007/s40473-017-0105-x.Peer-Reviewed Original ResearchCognitive processesTobacco use disorderAutomatic cognitive processesExecutive cognitive processesApproach-avoidance taskTranscranial direct current stimulationUse disordersDirect current stimulationExecutive processesAutomatic cognitionCognitive improvementCognitive functionNeurocognitive functionCurrent stimulationDistinct literaturesFuture researchTreatment targetsCognitionFurther researchDisordersRecent FindingsThereResearchBeneficial effectsTaskSmall samples