2024
Effects of exercise or metformin on myokine concentrations in patients with breast and colorectal cancer: A phase II multi‐centre factorial randomized trial
Brown J, Spielmann G, Yang S, Compton S, Jones L, Irwin M, Ligibel J, Meyerhardt J. Effects of exercise or metformin on myokine concentrations in patients with breast and colorectal cancer: A phase II multi‐centre factorial randomized trial. Journal Of Cachexia Sarcopenia And Muscle 2024 PMID: 38887915, DOI: 10.1002/jcsm.13509.Peer-Reviewed Original ResearchAerobic exerciseMyokine concentrationsStage I-III breastColorectal cancer survivorsEffects of exerciseColorectal cancerLinear mixed-effects regression modelsMixed-effects regression modelsCancer survivorsPhysical activityType I error rateExerciseMyokinesPilot studyRegression modelsCancer patientsRandomized trialsHypothesis-generating analysisMultiple comparisonsBreastSkeletal muscleInterleukin-15Clinical outcomesCancerPatients
2023
A review of the impact of energy balance on triple-negative breast cancer
Akingbesote N, Owusu D, Liu R, Cartmel B, Ferrucci L, Zupa M, Lustberg M, Sanft T, Blenman K, Irwin M, Perry R. A review of the impact of energy balance on triple-negative breast cancer. JNCI Monographs 2023, 2023: 104-124. PMID: 37139977, DOI: 10.1093/jncimonographs/lgad011.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTriple-negative breast cancerInterventional studyBreast cancerCancer treatmentClinical interventional studyClinical observationalImmune activationCancer outcomesCancer careClinical studiesOverall healthEnergy intakeNarrative reviewCancer cellsEnergy expenditureCancerTreatmentEnergy balanceOutcomesExerciseReviewDetrimental effectsImmunotherapyStudyIntake
2022
Effect of Exercise on Sarcopenia among Cancer Survivors: A Systematic Review
Cao A, Ferrucci LM, Caan BJ, Irwin ML. Effect of Exercise on Sarcopenia among Cancer Survivors: A Systematic Review. Cancers 2022, 14: 786. PMID: 35159052, PMCID: PMC8833677, DOI: 10.3390/cancers14030786.Peer-Reviewed Original Research
2012
Benefits of Aerobic and Resistance Exercise for Cancer Survivors
Irwin M. Benefits of Aerobic and Resistance Exercise for Cancer Survivors. Energy Balance And Cancer 2012, 199-214. DOI: 10.1007/978-1-4614-4493-0_12.Peer-Reviewed Original ResearchCancer outcomesPhysical activityCancer survivorsResistance exerciseSpecific cancer outcomesCancer diagnosisBenefits of exerciseQuality of lifeDiagnosis of cancerFuture exercise interventionsExercise interventionPhysical functioningLower riskSide effectsMore effective strategiesDiagnosisOutcomesExerciseCancerSurvivorsOverall qualitySurgeryRecurrenceEffective strategyActivity