2019
Complication Profiles by Mastectomy Indication in Tissue Expander Breast Reconstruction
Chouairi F, Gabrick KS, Avraham T, Markov NP, Alperovich M. Complication Profiles by Mastectomy Indication in Tissue Expander Breast Reconstruction. Plastic & Reconstructive Surgery 2019, Publish Ahead of Print: &na;. PMID: 30730496, DOI: 10.1097/prs.0000000000005423.Peer-Reviewed Original ResearchConceptsMastectomy flap necrosisTwo-stage implant breast reconstructionImplant breast reconstructionFlap necrosisBreast reconstructionHigh riskProphylactic mastectomyTherapeutic mastectomyMastectomy indicationExact testTissue expander breast reconstructionCLINICAL QUESTION/LEVELYale-New Haven HospitalPermanent implant reconstructionExpander breast reconstructionTimes higher riskFisher's exact testNew Haven HospitalSignificant differencesBreast reconstruction proceduresBinary logistic regressionReconstructive complicationsBreast groupPerioperative complicationsComplication ratePersistent disparities in breast cancer surgical outcomes among hispanic and African American patients
Mets EJ, Chouairi FK, Gabrick KS, Avraham T, Alperovich M. Persistent disparities in breast cancer surgical outcomes among hispanic and African American patients. European Journal Of Surgical Oncology 2019, 45: 584-590. PMID: 30683449, DOI: 10.1016/j.ejso.2019.01.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAsianBlack or African AmericanBreast NeoplasmsChemotherapy, AdjuvantComorbidityDiabetes MellitusFemaleHealth Status DisparitiesHispanic or LatinoHospitals, High-VolumeHospitals, UniversityHumansHypertensionMammaplastyMastectomyMiddle AgedNeoadjuvant TherapyObesityPostoperative ComplicationsRadiotherapy, AdjuvantSmokingTreatment OutcomeWhite PeopleConceptsAfrican American patientsAmerican patientsNeoadjuvant chemotherapyComplication ratePost-surgical complication rateHigher overall complication rateHigh rateHigher comorbidity burdenOverall complication ratePrior abdominal surgeryASA class IIIMastectomy flap necrosisRecords of patientsNipple-sparing mastectomyUniversity-affiliated hospitalCancer surgical outcomesHistory of radiationBreast cancer profilesComorbidity burdenReconstructive complicationsPrior radiationOncologic characteristicsPatient demographicsAbdominal surgeryBreast mastectomy
2017
Does Smoking History Confer a Higher Risk for Reconstructive Complications in Nipple‐Sparing Mastectomy?
Frey JD, Alperovich M, Levine JP, Choi M, Karp NS. Does Smoking History Confer a Higher Risk for Reconstructive Complications in Nipple‐Sparing Mastectomy? The Breast Journal 2017, 23: 415-420. PMID: 28097778, DOI: 10.1111/tbj.12760.Peer-Reviewed Original ResearchConceptsPack-year smoking historyNipple-sparing mastectomyComplete NAC necrosisHistory of smokingSmoking historyReconstructive complicationsNAC necrosisHigh riskNipple-areola complex necrosisNew York University Langone Medical CenterPack-year historyMastectomy flap necrosisActive smokersFlap necrosisRisk factorsMedical CenterReconstructive outcomesComplicationsMastectomyNecrosisNonsmokersOutcomesSmokersSmokingPatients
2016
“Breast in a Day”
Choi M, Frey JD, Alperovich M, Levine JP, Karp NS. “Breast in a Day”. Plastic & Reconstructive Surgery 2016, 138: 184e-191e. PMID: 27465178, DOI: 10.1097/prs.0000000000002333.Peer-Reviewed Original ResearchConceptsPermanent implant reconstructionNipple-sparing mastectomyMastectomy flap necrosisImplant reconstructionAcellular dermal matrixComplication rateFlap necrosisMajor mastectomy flap necrosisMinor mastectomy flap necrosisDermal matrixImplant sizeCLINICAL QUESTION/LEVELPercent of reconstructionsCommon major complicationPrior radiation therapyGreater complication rateLow complication rateNipple-sparing mastectomiesBody mass indexCommon minor complicationAverage implant sizeMajority of implantsOverall complicationsNipple necrosisMinor complications
2015
Breast Reconstruction Using Contour Fenestrated AlloDerm
Frey JD, Alperovich M, Weichman KE, Wilson SC, Hazen A, Saadeh PB, Levine JP, Choi M, Karp NS. Breast Reconstruction Using Contour Fenestrated AlloDerm. Plastic & Reconstructive Surgery Global Open 2015, 3: e505. PMID: 26495218, PMCID: PMC4596430, DOI: 10.1097/gox.0000000000000482.Peer-Reviewed Original ResearchMinor mastectomy flap necrosisMastectomy flap necrosisBreast reconstructionAcellular dermal matrixFlap necrosisReconstructive outcomesInfection outcomesInfection rateSignificant independent risk factorsDermal matrixImplant-based breast reconstructionPermanent implant reconstructionIndependent risk factorNipple-sparing mastectomyLow infection rateUse AlloDermIntravenous antibioticsImplant coverageRisk factorsImplant reconstructionPatientsAlloDermOutcomesNecrosisInfection
2014
Reconstructive Approach for Patients With Augmentation Mammaplasty Undergoing Nipple-Sparing Mastectomy
Alperovich M, Choi M, Frey JD, Karp NS. Reconstructive Approach for Patients With Augmentation Mammaplasty Undergoing Nipple-Sparing Mastectomy. Aesthetic Surgery Journal 2014, 34: 1059-1065. PMID: 25028736, DOI: 10.1177/1090820x14541958.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyReconstructive complicationsNipple-areola complexNAC necrosisComplete NAC necrosisPartial NAC necrosisPrevious breast augmentationMastectomy flap necrosisNew York University Langone Medical CenterImplant-based reconstructionMicrovascular free flapsBreast cellulitisNSM reconstructionPrevious augmentationPrior augmentationPatient characteristicsFlap necrosisMedical recordsMinimal complicationsPartial necrosisProphylactic managementCapsular contractureFisher's exactBreast cancerLarge cohortNipple-Sparing Mastectomy in Patients with Prior Breast Irradiation
Alperovich M, Choi M, Frey JD, Lee ZH, Levine JP, Saadeh PB, Shapiro RL, Axelrod DM, Guth AA, Karp NS. Nipple-Sparing Mastectomy in Patients with Prior Breast Irradiation. Plastic & Reconstructive Surgery 2014, 134: 202e-206e. PMID: 25068341, DOI: 10.1097/prs.0000000000000321.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyNipple-areola complex necrosisPrior breast irradiationMastectomy flap necrosisHigh-risk procedureBreast irradiationFlap necrosisComplete nipple-areola complex necrosisNipple-sparing mastectomy patientsHigh-risk patientsBody mass indexLatissimus dorsi flapMicrovascular free flapsSignificant differencesMastectomy cohortComplex complicationsImplant explantationMass indexMastectomy patientsCapsular contracturePartial necrosisAutologous reconstructionComplete necrosisIrradiated groupFree flap
2013
Nipple-Sparing Mastectomy in Patients with a History of Reduction Mammaplasty or Mastopexy
Alperovich M, Tanna N, Samra F, Blechman KM, Shapiro RL, Guth AA, Axelrod DM, Choi M, Karp NS. Nipple-Sparing Mastectomy in Patients with a History of Reduction Mammaplasty or Mastopexy. Plastic & Reconstructive Surgery 2013, 131: 962-967. PMID: 23629078, DOI: 10.1097/prs.0b013e3182865ad2.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyAuthors' institutionMean body mass indexCLINICAL QUESTION/LEVELMastectomy flap necrosisSubset of patientsNipple-sparing mastectomiesBody mass indexBreast cancer recurrenceLatissimus dorsi flapPresence of cancerNipple-areola complexMass indexProphylactic indicationsFlap necrosisMean agePatient populationBiopsy resultsMastectomy patientsTherapeutic resectionCancer recurrenceNipple viabilityReconstructive outcomesMastectomyReduction mammaplasty