2024
Safety Profile Comparison of 2 Smooth Tissue Expander Types
Almeida M, Alper D, Williams M, Shah R, Ihnat J, Hu K, Parikh N, Alperovich M. Safety Profile Comparison of 2 Smooth Tissue Expander Types. Annals Of Plastic Surgery 2024, 93: 178-182. PMID: 38980932, DOI: 10.1097/sap.0000000000004019.Peer-Reviewed Original ResearchConceptsBody mass indexComplication rateDrain durationMass indexAcellular dermal matrix useRetrospective review of patientsReview of patientsHigher body mass indexSmooth tissue expandersPain scoresChemotherapy exposureRetrospective reviewCapsular contractureSmooth implantsSafety profileWound breakdownFilling volumePatient comorbiditiesPerioperative informationCancer characteristicsMultivariate analysisComplicationsTissue expanderRadiation exposureMatrix use
2023
Breast implant capsule-associated squamous cell carcinoma: A systematic review and individual patient data meta-analysis
Yeow M, Ching A, Guillon C, Alperovich M. Breast implant capsule-associated squamous cell carcinoma: A systematic review and individual patient data meta-analysis. Journal Of Plastic Reconstructive & Aesthetic Surgery 2023, 86: 24-32. PMID: 37666057, DOI: 10.1016/j.bjps.2023.08.002.Peer-Reviewed Original ResearchMeSH KeywordsBreastBreast ImplantationBreast ImplantsBreast NeoplasmsCarcinoma, Squamous CellFemaleHumansMiddle AgedConceptsIndividual patient dataSCC diagnosisPatient dataSystematic reviewJoanna Briggs Institute critical appraisal toolsDisease-free survivalMajority of patientsSquamous cell carcinomaRisk of biasRisk of malignancyCritical appraisal toolExtracapsular spreadMean followOverall survivalMedian ageMedian timeCell carcinomaBreast implantationImplant removalPatientsBreast augmentationUS FoodDrug AdministrationBreast implantsAppraisal tool
2020
Worse overall health status negatively impacts satisfaction with breast reconstruction
Mehta SK, Olawoyin O, Chouairi F, Duy PQ, Mets EJ, Gabrick KS, Le NK, Avraham T, Alperovich M. Worse overall health status negatively impacts satisfaction with breast reconstruction. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 73: 2056-2062. PMID: 32972879, DOI: 10.1016/j.bjps.2020.08.093.Peer-Reviewed Original ResearchConceptsBREAST-Q scoresPatient-reported outcomesOverall health statusBreast reconstructionOverall healthASA classificationHealth statusGeneral linear modelAnesthesiologists physical status classificationYale-New Haven HospitalWorse overall health statusBREAST-Q outcomesHealth-related qualityPhysical status classificationNew Haven HospitalEffect of ASAASA 1Independent predictorsPatient factorsPostoperative satisfactionBreast surgeryPatient satisfactionASA 2PatientsRelevant covariatesRadiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management.
Gabrick K, Smetona J, Iyengar R, Dinis J, Chouiari F, Peck CJ, Persing J, Alperovich M. Radiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management. Journal Of Craniofacial Surgery 2020, 31: e388-e391. PMID: 32176015, DOI: 10.1097/scs.0000000000006356.Peer-Reviewed Original ResearchConceptsOrbital floor fracture managementOrbital floor fracturesPercent of patientsNon-operative managementPsychosocial distressFloor fracturesRadiographic findingsFracture managementMaxillary sinusYale-New Haven HospitalRight-sided fracturesAppearance-related psychosocial distressInferior rectus muscleLong-term outcomesPatient-reported questionnaireRectus muscle belliesMultiple surgical subspecialtiesNew Haven HospitalMean fracture areaBony injuriesInferior rectusOperative indicationsClinical findingsCommon injuriesMean durationMicrosurgery in the sickle cell trait population: is it actually safe?
Abraham PF, Allam O, Park KE, Alperovich M. Microsurgery in the sickle cell trait population: is it actually safe? BMJ Case Reports 2020, 13: e234924. PMID: 32381529, PMCID: PMC7222880, DOI: 10.1136/bcr-2020-234924.Peer-Reviewed Original ResearchConceptsSickle cell traitCell traitSickle cell disease patientsSickle cell trait patientsPoor vascular flowPostoperative day 2Indocyanine green angiographySickle cell diseaseMicrovascular free flapsSickle cell disease populationVenous congestionDisease patientsGreen angiographyVenous anastomosisCell diseaseMicrovascular compromiseDisease populationFree flapPatent anastomosisDay 2Flap transferVascular flowArterial Doppler signalsPatientsOperating roomClassification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis. Journal Of Craniofacial Surgery 2020, 31: 678-684. PMID: 32068731, DOI: 10.1097/scs.0000000000006173.Peer-Reviewed Original ResearchConceptsClass IIICrouzon syndromeClass IClass IISuture involvementSuture synostosisSimilar craniofacial characteristicsComputed tomography scanClassification of subtypesSurgical interventionMorphology of patientsAnatomic deformityTomography scanSurgical techniqueCT scanDifferent subtypesSagittal synostosisSyndromeClass IVPremature closureCraniofacial characteristicsSevere craniofacial malformationsCranial base lengthSynostosisDifferent pathologiesImpact of Insurance Payer on Type of Breast Reconstruction Performed.
Chouairi F, Mets EJ, Gabrick KS, Dinis J, Avraham T, Alperovich M. Impact of Insurance Payer on Type of Breast Reconstruction Performed. Plastic & Reconstructive Surgery 2020, 145: 1e-8e. PMID: 31881596, DOI: 10.1097/prs.0000000000006315.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHumansIncomeInsurance, HealthMammaplastyMiddle AgedSocioeconomic FactorsUnited StatesConceptsBreast reconstructionBreast reconstruction modalityAcademic medical centerOdds ratioMedical CenterMuscle-sparing transverse rectus abdominis myocutaneous flapPerforator flapTissue expander/implant breast reconstructionExpander/implant breast reconstructionMicrovascular autologous breast reconstructionTransverse rectus abdominis myocutaneous flapPerforator flap breast reconstructionIncome quartileCLINICAL QUESTION/LEVELReconstruction modalitiesSame academic medical centerRectus abdominis myocutaneous flapAutologous breast reconstructionFlap breast reconstructionImplant breast reconstructionHighest income quartileLowest income quartileInsurance typeMicrovascular reconstructionChi-square analysis
2019
Association of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome.
Lu X, Jorge Forte A, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Association of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome. Plastic & Reconstructive Surgery 2019, 143: 1233e-1243e. PMID: 31136487, DOI: 10.1097/prs.0000000000005643.Peer-Reviewed Original ResearchMandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Mandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome. Annals Of Plastic Surgery 2019, 83: 568-582. PMID: 31008788, DOI: 10.1097/sap.0000000000001811.Peer-Reviewed Original ResearchComplication Profiles by Mastectomy Indication in Tissue Expander Breast Reconstruction
Chouairi F, Gabrick KS, Avraham T, Markov NP, Alperovich M. Complication Profiles by Mastectomy Indication in Tissue Expander Breast Reconstruction. Plastic & Reconstructive Surgery 2019, Publish Ahead of Print: &na;. PMID: 30730496, DOI: 10.1097/prs.0000000000005423.Peer-Reviewed Original ResearchConceptsMastectomy flap necrosisTwo-stage implant breast reconstructionImplant breast reconstructionFlap necrosisBreast reconstructionHigh riskProphylactic mastectomyTherapeutic mastectomyMastectomy indicationExact testTissue expander breast reconstructionCLINICAL QUESTION/LEVELYale-New Haven HospitalPermanent implant reconstructionExpander breast reconstructionTimes higher riskFisher's exact testNew Haven HospitalSignificant differencesBreast reconstruction proceduresBinary logistic regressionReconstructive complicationsBreast groupPerioperative complicationsComplication rateChronic steroid use as an independent risk factor for perioperative complications
Chouairi F, Torabi SJ, Mercier MR, Gabrick KS, Alperovich M. Chronic steroid use as an independent risk factor for perioperative complications. Surgery 2019, 165: 990-995. PMID: 30765140, DOI: 10.1016/j.surg.2018.12.016.Peer-Reviewed Original ResearchConceptsChronic steroid useSteroid useSurgical outcomesChronic steroidsPerioperative outcomesNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseLogistic regressionPerioperative surgical outcomesImprovement Program databaseIndependent risk factorRisk of readmissionPoor perioperative outcomesRisk of reoperationPoor surgical outcomesRisk of deathMore comorbiditiesCorticosteroid usePerioperative complicationsPatient demographicsSurgical cohortSurgical complicationsSurgical patientsRisk factorsOdds ratioPersistent disparities in breast cancer surgical outcomes among hispanic and African American patients
Mets EJ, Chouairi FK, Gabrick KS, Avraham T, Alperovich M. Persistent disparities in breast cancer surgical outcomes among hispanic and African American patients. European Journal Of Surgical Oncology 2019, 45: 584-590. PMID: 30683449, DOI: 10.1016/j.ejso.2019.01.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAsianBlack or African AmericanBreast NeoplasmsChemotherapy, AdjuvantComorbidityDiabetes MellitusFemaleHealth Status DisparitiesHispanic or LatinoHospitals, High-VolumeHospitals, UniversityHumansHypertensionMammaplastyMastectomyMiddle AgedNeoadjuvant TherapyObesityPostoperative ComplicationsRadiotherapy, AdjuvantSmokingTreatment OutcomeWhite PeopleConceptsAfrican American patientsAmerican patientsNeoadjuvant chemotherapyComplication ratePost-surgical complication rateHigher overall complication rateHigh rateHigher comorbidity burdenOverall complication ratePrior abdominal surgeryASA class IIIMastectomy flap necrosisRecords of patientsNipple-sparing mastectomyUniversity-affiliated hospitalCancer surgical outcomesHistory of radiationBreast cancer profilesComorbidity burdenReconstructive complicationsPrior radiationOncologic characteristicsPatient demographicsAbdominal surgeryBreast mastectomy
2018
Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome. International Journal Of Oral And Maxillofacial Surgery 2018, 48: 309-321. PMID: 30389113, DOI: 10.1016/j.ijom.2018.10.013.Peer-Reviewed Original ResearchConceptsCrouzon syndromeCT scanAnteroposterior lengthWidth of maxillaPreoperative CT scanMonths-2 yearsMonths of agePrincipal deformityControl subjectsGlobe projectionAge subgroupsMaxillary wideningSecondary deformitiesOrbital wallAnterior protrusionSyndromeFacial malformationsMonthsDeformityAnteroposterior positionZygomatic regionCranial baseZygomaMalformationsMaterialise softwareEvolution in Monitoring of Free Flap Autologous Breast Reconstruction after Nipple-Sparing Mastectomy
Frey JD, Stranix JT, Chiodo MV, Alperovich M, Ahn CY, Allen RJ, Choi M, Karp NS, Levine JP. Evolution in Monitoring of Free Flap Autologous Breast Reconstruction after Nipple-Sparing Mastectomy. Plastic & Reconstructive Surgery 2018, 141: 1086-1093. PMID: 29659449, DOI: 10.1097/prs.0000000000004271.Peer-Reviewed Original ResearchMeSH KeywordsAdultBreastBreast NeoplasmsFemaleFree Tissue FlapsHumansMammaplastyMastectomy, SubcutaneousMiddle AgedNipplesPatient SatisfactionPerforator FlapPostoperative CarePostoperative ComplicationsReoperationRetrospective StudiesTransplantation, AutologousTreatment OutcomeUltrasonography, DopplerConceptsNipple-sparing mastectomyFree flap reconstructionSkin paddleFlap reconstructionAutologous reconstructionRevision proceduresMuscle-sparing transverse rectus abdominis myocutaneous flapFree flap autologous breast reconstructionAutologous free flap reconstructionTransverse rectus abdominis myocutaneous flapGreater body mass indexCLINICAL QUESTION/LEVELPercentage of flapsProfunda artery perforatorRectus abdominis myocutaneous flapAutologous breast reconstructionBody mass indexInferior epigastric perforatorGreater mean numberMass indexFlap weightMastectomy weightComparing outcomesBreast reconstructionMastectomy reconstruction
2017
Does Smoking History Confer a Higher Risk for Reconstructive Complications in Nipple‐Sparing Mastectomy?
Frey JD, Alperovich M, Levine JP, Choi M, Karp NS. Does Smoking History Confer a Higher Risk for Reconstructive Complications in Nipple‐Sparing Mastectomy? The Breast Journal 2017, 23: 415-420. PMID: 28097778, DOI: 10.1111/tbj.12760.Peer-Reviewed Original ResearchConceptsPack-year smoking historyNipple-sparing mastectomyComplete NAC necrosisHistory of smokingSmoking historyReconstructive complicationsNAC necrosisHigh riskNipple-areola complex necrosisNew York University Langone Medical CenterPack-year historyMastectomy flap necrosisActive smokersFlap necrosisRisk factorsMedical CenterReconstructive outcomesComplicationsMastectomyNecrosisNonsmokersOutcomesSmokersSmokingPatients
2016
Outpatient Alveolar Bone Grafting
Farber SJ, Runyan CM, Stern MJ, Massie JP, Alperovich M, Flores RL. Outpatient Alveolar Bone Grafting. Journal Of Craniofacial Surgery 2016, 27: 1661-1664. PMID: 27438449, DOI: 10.1097/scs.0000000000002899.Peer-Reviewed Original ResearchConceptsAlveolar bone graftTotal direct costsVariable direct costsInpatient stayObservation groupSite painDirect costsOutpatient costsRetrospective single-institution reviewDonor site painGroup of patientsSame-day dischargeSingle-institution reviewPostoperative inpatient stayOperating room costsCost-efficient treatmentHospital stayInpatient costsOutpatient groupTrephine techniqueAlveolar boneABG surgeryBone graftStayRoom costs“Breast in a Day”
Choi M, Frey JD, Alperovich M, Levine JP, Karp NS. “Breast in a Day”. Plastic & Reconstructive Surgery 2016, 138: 184e-191e. PMID: 27465178, DOI: 10.1097/prs.0000000000002333.Peer-Reviewed Original ResearchConceptsPermanent implant reconstructionNipple-sparing mastectomyMastectomy flap necrosisImplant reconstructionAcellular dermal matrixComplication rateFlap necrosisMajor mastectomy flap necrosisMinor mastectomy flap necrosisDermal matrixImplant sizeCLINICAL QUESTION/LEVELPercent of reconstructionsCommon major complicationPrior radiation therapyGreater complication rateLow complication rateNipple-sparing mastectomiesBody mass indexCommon minor complicationAverage implant sizeMajority of implantsOverall complicationsNipple necrosisMinor complicationsApplying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair
Alperovich M, Frey JD, Potts MB, Riina HA, Staffenberg DA. Applying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair. Journal Of Craniofacial Surgery 2016, 27: 1077-1079. PMID: 27192638, DOI: 10.1097/scs.0000000000002643.Peer-Reviewed Original ResearchConceptsCraniofacial principlesNeurosurgical exposureCraniofacial surgeonsZygomaticomaxillary complex fracturesSuperior cosmetic resultsAnterior skull baseRisk of injuryAneurysm repairNerve transectionCosmetic resultsFacial nerveEyebrow incisionPeriorbital surgeryFrontal branchSkull baseConspicuous scarringTranspalpebral approachComplex fracturesNeurosurgical literatureSeries experienceSurgeonsCraniofacial surgerySurgeryCraniotomyExposure
2015
Oncologic outcomes after nipple‐sparing mastectomy: A single‐institution experience
Frey JD, Alperovich M, Kim JC, Axelrod DM, Shapiro RL, Choi M, Schnabel FR, Karp NS, Guth AA. Oncologic outcomes after nipple‐sparing mastectomy: A single‐institution experience. Journal Of Surgical Oncology 2015, 113: 8-11. PMID: 26628318, DOI: 10.1002/jso.24097.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomySkin-sparing mastectomyOncologic outcomesLong-term oncologic outcomesAverage patient ageCommon histologic typePercent of patientsLocoregional recurrence rateSingle institution experienceAverage tumor sizeChest wall recurrenceInvasive ductal carcinomaLocoregional recurrencePatient ageHistologic typeDuctal carcinomaRecurrence rateTumor sizeAverage patientPatientsTherapeutic indicationsMastectomyRecurrenceOutcomesComplex recurrence
2014
Reconstructive Approach for Patients With Augmentation Mammaplasty Undergoing Nipple-Sparing Mastectomy
Alperovich M, Choi M, Frey JD, Karp NS. Reconstructive Approach for Patients With Augmentation Mammaplasty Undergoing Nipple-Sparing Mastectomy. Aesthetic Surgery Journal 2014, 34: 1059-1065. PMID: 25028736, DOI: 10.1177/1090820x14541958.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyReconstructive complicationsNipple-areola complexNAC necrosisComplete NAC necrosisPartial NAC necrosisPrevious breast augmentationMastectomy flap necrosisNew York University Langone Medical CenterImplant-based reconstructionMicrovascular free flapsBreast cellulitisNSM reconstructionPrevious augmentationPrior augmentationPatient characteristicsFlap necrosisMedical recordsMinimal complicationsPartial necrosisProphylactic managementCapsular contractureFisher's exactBreast cancerLarge cohort