2007
Characterization of Early Stages of Human B Cell Development by Gene Expression Profiling
Hystad ME, Myklebust JH, Bø TH, Sivertsen EA, Rian E, Forfang L, Munthe E, Rosenwald A, Chiorazzi M, Jonassen I, Staudt LM, Smeland EB. Characterization of Early Stages of Human B Cell Development by Gene Expression Profiling. The Journal Of Immunology 2007, 179: 3662-3671. PMID: 17785802, DOI: 10.4049/jimmunol.179.6.3662.Peer-Reviewed Original ResearchConceptsHuman B cell developmentB cell developmentGene expression profilingCell developmentTranscription factorsExpression profilingHemopoietic stem cellsLineage-associated transcription factorsInteresting expression patternsStem cellsMyeloid-associated genesExpression of genesAdult bone marrowFunctional assignmentImmature B cellsKey genesCDNA microarrayGene setsExpression patternsVDJ recombinationUnknown roleB-lymphoid cellsGenesB cellsRNA amplification
2003
Molecular Diagnosis of Primary Mediastinal B Cell Lymphoma Identifies a Clinically Favorable Subgroup of Diffuse Large B Cell Lymphoma Related to Hodgkin Lymphoma
Rosenwald A, Wright G, Leroy K, Yu X, Gaulard P, Gascoyne RD, Chan WC, Zhao T, Haioun C, Greiner TC, Weisenburger DD, Lynch JC, Vose J, Armitage JO, Smeland EB, Kvaloy S, Holte H, Delabie J, Campo E, Montserrat E, Lopez-Guillermo A, Ott G, Muller-Hermelink HK, Connors JM, Braziel R, Grogan TM, Fisher RI, Miller TP, LeBlanc M, Chiorazzi M, Zhao H, Yang L, Powell J, Wilson WH, Jaffe ES, Simon R, Klausner RD, Staudt LM. Molecular Diagnosis of Primary Mediastinal B Cell Lymphoma Identifies a Clinically Favorable Subgroup of Diffuse Large B Cell Lymphoma Related to Hodgkin Lymphoma. Journal Of Experimental Medicine 2003, 198: 851-862. PMID: 12975453, PMCID: PMC2194208, DOI: 10.1084/jem.20031074.Peer-Reviewed Original ResearchMeSH KeywordsAdultChromosomes, Human, Pair 19Diagnosis, DifferentialGene Expression ProfilingHodgkin DiseaseHumansLymphoma, B-CellLymphoma, Large B-Cell, DiffuseMediastinal NeoplasmsMiddle AgedMolecular Diagnostic TechniquesOligonucleotide Array Sequence AnalysisSurvival RateTreatment OutcomeTumor Cells, CulturedConceptsGene expressionHodgkin's lymphoma cellsGenomic lociNeighboring genesMolecular diagnosisPMBL patientsPrimary mediastinal B-cell lymphomaLymphoma cellsHodgkin's lymphoma cell linesLymphoma cell linesDiffuse large B-cell lymphomaDevelopment of therapiesGenesT cell activationPrecise molecular diagnosisCell linesB-cell lymphomaMediastinal B-cell lymphomaLarge B-cell lymphomaCell activationCell lymphomaExpressionHodgkin's lymphomaDLBCL patientsCells