2013
Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma
Chiorazzi M, Rui L, Yang Y, Ceribelli M, Tishbi N, Maurer CW, Ranuncolo SM, Zhao H, Xu W, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Delabie J, Rimsza LM, Shaham S, Staudt LM. Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 3943-3948. PMID: 23431138, PMCID: PMC3593917, DOI: 10.1073/pnas.1217271110.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsApoptosisBase SequenceCaenorhabditis elegansCaenorhabditis elegans ProteinsCaspasesCell Line, TumorEnzyme ActivationF-Box ProteinsHEK293 CellsHumansLymphomaLymphoma, Large B-Cell, DiffuseMolecular Sequence DataMutation, MissenseProto-Oncogene Proteins c-bcl-2Repressor ProteinsRNA, MessengerRNA, NeoplasmSequence Homology, Amino AcidConceptsCED-9Cell deathCaenorhabditis elegansDRE-1Caspase CED-3Control cell deathApoptotic cell deathRegulators of apoptosisEGL-1CED-3Cell fateHuman diffuse large B-cell lymphomaHuman proteinsCaspase activationFBXO10BCL2 proteinElegansProteinHuman malignanciesHuman lymphomasAlternative mechanismApoptosisActivationBH3Regulator
2003
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma
Rosenwald A, Wright G, Wiestner A, Chan C, Connors JM, Campo E, Gascoyne RD, Grogan TM, Muller-Hermelink HK, Smeland EB, Chiorazzi M, Giltnane JM, Hurt EM, Zhao H, Averett L, Henrickson S, Yang L, Powell J, Wilson WH, Jaffe ES, Simon R, Klausner RD, Montserrat E, Bosch F, Greiner TC, Weisenburger DD, Sanger WG, Dave BJ, Lynch JC, Vose J, Armitage JO, Fisher RI, Miller TP, LeBlanc M, Ott G, Kvaloy S, Holte H, Delabie J, Staudt LM. The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell 2003, 3: 185-197. PMID: 12620412, DOI: 10.1016/s1535-6108(03)00028-x.Peer-Reviewed Original ResearchMeSH KeywordsADP-Ribosylation FactorsAdultAgedAged, 80 and overAtaxia Telangiectasia Mutated ProteinsCell Cycle ProteinsCyclin D1Cyclin-Dependent Kinase Inhibitor p16DNA-Binding ProteinsFemaleGene Expression ProfilingGenes, NeoplasmHumansLymphoma, Mantle-CellMaleMiddle AgedNeoplasm ProteinsPrognosisProtein Serine-Threonine KinasesReverse Transcriptase Polymerase Chain ReactionRNA, MessengerRNA, NeoplasmSurvival RateTumor Suppressor Protein p53Tumor Suppressor ProteinsUntranslated RegionsConceptsMantle cell lymphoma