PDTM-35. GENETIC ALTERATIONS DRIVING SPINAL INTRAMEDULLARY METASTASES OF A HISTONE-MUTATED DIFFUSE MIDLINE PINEAL GLIOMA
Hong C, Kundishora A, Omay E, Huttner A, Marks A, Diluna M, Kahle K. PDTM-35. GENETIC ALTERATIONS DRIVING SPINAL INTRAMEDULLARY METASTASES OF A HISTONE-MUTATED DIFFUSE MIDLINE PINEAL GLIOMA. Neuro-Oncology 2018, 20: vi211-vi211. PMCID: PMC6217703, DOI: 10.1093/neuonc/noy148.875.Peer-Reviewed Original ResearchDiffuse midline gliomaMidline gliomaH3K27M mutationGenetic alterationsM mutationIntramedullary spinal metastasesSpinal intramedullary metastasisDistant metastatic spreadLower extremity weaknessMismatch repair gene mutationsKey driver mutationsRepair gene mutationsProton beam radiationWhole-exome sequencing