2022
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis
Mai Y, Ouyang Y, Yu M, Qin Y, Girardi M, Saltzman WM, Cocco E, Zhao C, Yu L, Jia Y, Xiao L, Dou L, Deng W, Liu Y, Xie J, Deng Y. Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis. Journal Of Controlled Release 2022, 349: 354-366. PMID: 35817278, DOI: 10.1016/j.jconrel.2022.07.006.Peer-Reviewed Original ResearchConceptsHealthy skinPsoriasis treatmentTopical formulationsPsoriatic skinCurrent psoriasis treatmentsFirst-line treatmentSingle-dose cureLocal drug concentrationModerate psoriasisLesional skinSingle doseDermal atrophyTherapeutic levelsTherapeutic efficacyCorticosteroidsDrug concentrationsPsoriasisBNPBasal cellsSkin retentionSkinLesionsBioadhesive nanoparticlesTreatmentStratum corneum
2013
Case experience of 308-nm excimer laser therapy compatibility with PUVA and oral bexarotene for the treatment of cutaneous lesions in mycosis fungoides.
Huang J, Cowper S, Moss J, Girardi M. Case experience of 308-nm excimer laser therapy compatibility with PUVA and oral bexarotene for the treatment of cutaneous lesions in mycosis fungoides. Journal Of Drugs In Dermatology 2013, 12: 487-9. PMID: 23652902.Peer-Reviewed Case Reports and Technical NotesConceptsExcimer laser therapyOral bexaroteneLaser therapyMycosis fungoides lesionsMinimal side effectsMF plaquesLocal erythemaMycosis fungoidesTreatment regimenCutaneous lesionsMF lesionsHistologic resolutionSide effectsTherapyBexaroteneLesionsUltraviolet ARegimenPUVAPatientsTreatmentPlaquesCase experienceFungoidesErythema
2010
A transient epidermolysis bullosa simplex‐like phenotype associated with bexarotene treatment in a G138E KRT5 heterozygote
Trufant JW, Kreizenbeck GM, Carlson KR, Muthusamy V, Girardi M, Bosenberg MW. A transient epidermolysis bullosa simplex‐like phenotype associated with bexarotene treatment in a G138E KRT5 heterozygote. Journal Of Cutaneous Pathology 2010, 37: 1155-1160. PMID: 20849457, DOI: 10.1111/j.1600-0560.2010.01557.x.Peer-Reviewed Original ResearchConceptsBexarotene treatmentEpidermolysis bullosa simplexKeratinocyte lysisCutaneous T-cell lymphomaT-cell lymphomaPalmoplantar keratodermaIntraepidermal blister formationClinical subtypesClinical trialsDrug treatmentSide effectsMechanobullous disordersReticulate hyperpigmentationSkin fragilityLike phenotypeKeratin 5Genetic sequencingSimilar frequencyRare variantsFocal palmoplantar keratodermaBlister formationTreatmentKRT5 mutationKeratin synthesisKeratoderma
2003
Selective immmunotherapy through extracorporeal photochemotherapy: yesterday, today, and tomorrow
Girardi M, Knobler R, Edelson R. Selective immmunotherapy through extracorporeal photochemotherapy: yesterday, today, and tomorrow. Hematology/Oncology Clinics Of North America 2003, 17: 1391-1403. PMID: 14710891, DOI: 10.1016/s0889-8588(03)00106-0.Peer-Reviewed Original ResearchConceptsLow side effect profileSide effect profilePotential novel strategyMechanism of actionImmunosuppressive medicationsExtracorporeal photochemotherapyEffect profileTransplant rejectionTreatment of cancerClinical recordsRole of ECPClinical studiesT cellsTreatment considerationsModern therapeuticsTreatmentNovel strategyGVHDMedicationsAutoimmunityCTCLMalignancyECPTherapyCancer
2000
Cutaneous T-cell lymphoma: pathogenesis and treatment.
Girardi M, Edelson RL. Cutaneous T-cell lymphoma: pathogenesis and treatment. Oncology 2000, 14: 1061-70; discussion 1070-4, 1076. PMID: 10929591.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaSkin immune systemImmune systemT cellsManagement of CTCLCutaneous T-cellMemory T cellsT helper cellsT-cell lymphomaSelective adhesion moleculeLymph nodesClinical spectrumPeripheral bloodCutaneous pathogensMajor subtypesPathogenesisAdhesion moleculesLymphomaDistinctive subsetTreatmentNormal functioningCellsBetter understandingImmunosurveillanceMalignancyPostirradiation Morphea of the Breast Presentation of Two Cases and Review of the Literature
Schaffer J, Carroll C, Dvoretsky I, Huether M, Girardi M. Postirradiation Morphea of the Breast Presentation of Two Cases and Review of the Literature. Dermatology 2000, 200: 67-71. PMID: 10681621, DOI: 10.1159/000018322.Peer-Reviewed Original ResearchConceptsSupervoltage radiation therapyRadiation therapyPostirradiation morpheaBreast cancerSecond primary carcinomaSite of treatmentInfectious cellulitisResidual sclerosisConservative treatmentRecurrent carcinomaClinical presentationInflammatory componentMetastatic carcinomaPrimary carcinomaMorpheaNew casesCommon modalityMedical literatureCarcinomaTherapyPatientsCancerTreatmentPresentationYears
1999
Extracorporeal photochemotherapy in human and murine graft-versus-host disease
Girardi M, McNiff J, Heald P. Extracorporeal photochemotherapy in human and murine graft-versus-host disease. Journal Of Dermatological Science 1999, 19: 106-113. PMID: 10098701, DOI: 10.1016/s0923-1811(98)00066-8.Peer-Reviewed Original Research