2020
Opioid-Sparing Cardiac Anesthesia: Secondary Analysis of an Enhanced Recovery Program for Cardiac Surgery.
Grant M, Isada T, Ruzankin P, Gottschalk A, Whitman G, Lawton J, Dodd-O J, Barodka V. Opioid-Sparing Cardiac Anesthesia: Secondary Analysis of an Enhanced Recovery Program for Cardiac Surgery. Anesthesia & Analgesia 2020, 131: 1852-1861. PMID: 32889848, DOI: 10.1213/ane.0000000000005152.Peer-Reviewed Original ResearchConceptsIntraoperative opioid administrationEnhanced recovery programmeOpioid administrationCardiac surgeryNonopioid interventionsPostoperative outcomesNumber of interventionsOpioid patientsSecondary analysisSerratus anterior plane blockMorphine sulfate equivalentsOpioid-sparing strategiesPostoperative pain scoresFuture prospective studiesLength of stayLinear mixed-effects regression modelsMixed-effects regression modelsIntraoperative dexmedetomidineLower opioidPreoperative gabapentinMultimodal analgesiaPain scoresPostoperative complicationsOpioid usePlane block
2016
The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting
Grant M, Lee H, Page A, Hobson D, Wick E, Wu C. The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting. Survey Of Anesthesiology 2016, 60: 209-210. DOI: 10.1097/01.sa.0000490914.46103.7f.Peer-Reviewed Original ResearchThe Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting
Grant M, Lee H, Page A, Hobson D, Wick E, Wu C. The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2016, 122: 976-985. PMID: 26991615, DOI: 10.1213/ane.0000000000001120.Peer-Reviewed Original ResearchConceptsPreoperative gabapentinPrimary end pointEnd pointPostoperative nauseaSide effectsPrevention of PONVHigh-risk surgerySignificant reductionGabapentin administrationPostoperative sedationThiopental inductionOpioid analgesiaPostoperative painAntiemetic effectRepeat dosingGeneral anesthesiaSubgroup analysisPONVPooled effectNauseaVomitingGabapentinPrimary analysisSecondary analysisTrials