2019
Perioperative Dextrose Infusion and Postoperative Nausea and Vomiting
Zorrilla-Vaca A, Marmolejo-Posso D, Stone A, Li J, Grant MC. Perioperative Dextrose Infusion and Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2019, Publish Ahead of Print: &na;. PMID: 30649067, DOI: 10.1213/ane.0000000000004019.Peer-Reviewed Original ResearchConceptsPostoperative nauseaDextrose infusionAntiemetic administrationGlucose levelsPlasma glucose monitoringPostoperative antiemetic administrationRescue antiemetic requirementsFurther prospective trialsPostanesthesia care unitSerum glucose levelsPlasma glucose levelsSignificant reductionAntiemetic requirementsPostoperative hyperglycemiaProspective trialSecondary outcomesPostoperative infusionPrimary outcomeCare unitCochrane LibraryUse of dextroseNauseaVomitingInfusionSignificant associationPerioperative duloxetine for acute postoperative analgesia: a meta-analysis of randomized trials
Zorrilla-Vaca A, Stone A, Caballero-Lozada A, Paredes S, Grant M. Perioperative duloxetine for acute postoperative analgesia: a meta-analysis of randomized trials. Regional Anesthesia & Pain Medicine 2019, 44: 959-965. PMID: 31375539, DOI: 10.1136/rapm-2019-100687.Peer-Reviewed Original ResearchPostoperative nausea/vomitingAcute postoperative painPostoperative painOpioid administrationSide effectsSignificant reductionAcute perioperative painAcute postoperative analgesiaPostoperative opioid administrationChronic neuropathic painChronic postsurgical painEfficacy of duloxetineNausea/vomitingAdditional prospective studiesNorepinephrine reuptake inhibitorsMultimodal analgesic planDuloxetine usePerioperative duloxetinePostoperative analgesiaPostsurgical painMultimodal analgesiaNeuropathic painPain scoresPerioperative painAnalgesic plan
2017
Dedicated Operating Room Teams and Clinical Outcomes in an Enhanced Recovery after Surgery Pathway for Colorectal Surgery
Grant MC, Hanna A, Benson A, Hobson D, Wu CL, Yuan CT, Rosen M, Wick EC. Dedicated Operating Room Teams and Clinical Outcomes in an Enhanced Recovery after Surgery Pathway for Colorectal Surgery. Journal Of The American College Of Surgeons 2017, 226: 267-276. PMID: 29274837, DOI: 10.1016/j.jamcollsurg.2017.12.010.Peer-Reviewed Original ResearchConceptsClinical outcomesProcess measure complianceEnhanced recoveryMeasure complianceOperating room teamSurgery programAnesthesia providersSurgical site infectionLength of stayHigh complianceColorectal surgeryERAS implementationERAS programSite infectionPerioperative careSurgery pathwayProvider teamProtocol elementsNurse anesthetistsIndividual providersDedicated teamOutcomesSignificant increaseSignificant reductionAnesthesiologistsOptimizing an Enhanced Recovery Pathway Program: Development of a Postimplementation Audit Strategy
Grant M, Galante D, Hobson D, Lavezza A, Friedman M, Wu C, Wick E. Optimizing an Enhanced Recovery Pathway Program: Development of a Postimplementation Audit Strategy. The Joint Commission Journal On Quality And Patient Safety 2017, 43: 524-533. PMID: 28942777, DOI: 10.1016/j.jcjq.2017.02.011.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersClinical ProtocolsDigestive System Surgical ProceduresElectronic Health RecordsFemaleGroup ProcessesHumansLength of StayMaleMiddle AgedOrganizational CulturePatient Care BundlesPatient Care TeamPerioperative CarePostoperative ComplicationsQuality Indicators, Health CareRetrospective StudiesSafety ManagementConceptsLength of stayOverall LOSAverage LOSProcess measuresThree-month followProcess measure complianceAcademic medical centerSystem-level interventionsSignificant reductionElectronic health recordsColorectal surgeryConsecutive patientsPathway implementationEarly mobilityMeasure complianceMedical CenterPreventable harmOne-year periodPatientsRecovery pathwaysHealth recordsSystem-level changesSurgeryComplianceSame procedureImpact of Enhanced Recovery After Surgery and Fast Track Surgery Pathways on Healthcare-associated Infections
Grant M, Yang D, Wu C, Makary M, Wick E. Impact of Enhanced Recovery After Surgery and Fast Track Surgery Pathways on Healthcare-associated Infections. Annals Of Surgery 2017, 265: 68-79. PMID: 28009729, DOI: 10.1097/sla.0000000000001703.Peer-Reviewed Original ResearchConceptsHealthcare-associated infectionsSurgical site infectionUrinary tract infectionLung infectionFTS protocolFast-track surgery pathwaysFast-track surgery protocolMajor healthcare-associated infectionPostoperative lung infectionLength of staySignificant reductionPostoperative incidenceHospital lengthColorectal surgerySurgery protocolTract infectionsPerioperative carePrimary outcomeSite infectionRandomized trialsSurgery pathwayPelvic surgerySubgroup analysisSurgical careHigh risk
2016
The Effect of Preoperative Pregabalin on Postoperative Nausea and Vomiting
Grant M, Betz M, Hulse M, Zorrilla-Vaca A, Hobson D, Wick E, Wu C. The Effect of Preoperative Pregabalin on Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2016, 123: 1100-1107. PMID: 27464972, DOI: 10.1213/ane.0000000000001404.Peer-Reviewed Original ResearchConceptsPreoperative pregabalinPostoperative nauseaPostoperative visual disturbancesPrevention of PONVSimilar antiemetic efficacyHigh-risk surgerySignificant reductionAdjuvant medicationsAntiemetic efficacyProphylactic antiemeticsThiopental inductionOpioid analgesiaPostoperative painSurgery protocolVisual disturbancesRandomized trialsRepeat dosingGeneral anesthesiaSubgroup analysisPregabalinEnhanced recoveryPONVNauseaVomitingTrialsThe Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting
Grant M, Lee H, Page A, Hobson D, Wick E, Wu C. The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2016, 122: 976-985. PMID: 26991615, DOI: 10.1213/ane.0000000000001120.Peer-Reviewed Original ResearchConceptsPreoperative gabapentinPrimary end pointEnd pointPostoperative nauseaSide effectsPrevention of PONVHigh-risk surgerySignificant reductionGabapentin administrationPostoperative sedationThiopental inductionOpioid analgesiaPostoperative painAntiemetic effectRepeat dosingGeneral anesthesiaSubgroup analysisPONVPooled effectNauseaVomitingGabapentinPrimary analysisSecondary analysisTrials