2020
Adult Cardiac Surgery and the COVID-19 Pandemic: Aggressive Infection Mitigation Strategies Are Necessary in the Operating Room and Surgical Recovery
Engelman D, Lother S, George I, Funk D, Ailawadi G, Atluri P, Grant M, Haft J, Hassan A, Legare J, Whitman G, Arora R, Force T. Adult Cardiac Surgery and the COVID-19 Pandemic: Aggressive Infection Mitigation Strategies Are Necessary in the Operating Room and Surgical Recovery. The Annals Of Thoracic Surgery 2020, 110: 707-711. PMID: 32353440, PMCID: PMC7185911, DOI: 10.1016/j.athoracsur.2020.04.007.Peer-Reviewed Original Research
2016
A Meta-analysis of Intraoperative Ventilation Strategies to Prevent Pulmonary Complications
Yang D, Grant M, Stone A, Wu C, Wick E. A Meta-analysis of Intraoperative Ventilation Strategies to Prevent Pulmonary Complications. Annals Of Surgery 2016, 263: 881-887. PMID: 26720429, DOI: 10.1097/sla.0000000000001443.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureAcute lung injuryPostoperative lung infectionLung infectionLung ventilationLTV ventilationHospital stayHealthy patientsLow tidal volume mechanical ventilationPostoperative acute lung injuryIntermittent recruitment maneuverIntraoperative ventilation strategiesProtective lung ventilationLength of hospitalProtective ventilation strategyEnd-expiratory pressureVolume mechanical ventilationVentilation strategiesAnalysis of trialsPostoperative incidencePulmonary complicationsPulmonary outcomesProtective ventilationLung injuryRecruitment maneuvers
2008
Warm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition
Kon Z, Brown E, Grant M, Ozeki T, Burris N, Collins M, Kwon M, Poston R. Warm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition. European Journal Of Cardio-Thoracic Surgery 2008, 33: 215-221. PMID: 18068996, PMCID: PMC2605708, DOI: 10.1016/j.ejcts.2007.11.008.Peer-Reviewed Original ResearchConceptsPump coronary artery bypassCoronary artery bypassTranscardiac gradientCoronary occlusionArtery bypassMyocardial ischemiaTNF-alphaCoronary sinus bloodEarly graft failureRegional myocardial ischemiaProthrombotic stateGraft failureProtamine administrationSinus bloodConsecutive patientsIschemic injuryMyocardial injuryIL-8Warm ischemiaPathophysiologic consequencesSeries of biomarkersCoagulation systemOPCABIschemiaInflammation