2024
Association Between the Decipher Genomic Classifier and Prostate Cancer Outcome in the Real-world Setting
Leapman M, Ho J, Liu Y, Filson C, Zhao X, Hakansson A, Proudfoot J, Davicioni E, Martin D, An Y, Seibert T, Lin D, Spratt D, Cooperberg M, Sprenkle P, Ross A. Association Between the Decipher Genomic Classifier and Prostate Cancer Outcome in the Real-world Setting. European Urology Oncology 2024 PMID: 39098389, DOI: 10.1016/j.euo.2024.07.010.Peer-Reviewed Original ResearchDecipher genomic classifierRisk of metastasisBiochemical recurrenceRadical prostatectomyGenomic classifierDecipher testProstate cancerProstate Risk Assessment Postsurgical ScoreRisk of biochemical recurrencePatient's prostate cancerRisk of cancer recurrencePathological risk factorsProstate cancer outcomesCox proportional hazards regressionRetrospective cohort studyElectronic health record dataReal-world settingsProportional hazards regressionHealth record dataReal-world practice settingsProstate biopsyRP specimensOncological outcomesPrognostic significanceMedian age
2016
Application of a Prognostic Gleason Grade Grouping System to Assess Distant Prostate Cancer Outcomes
Leapman MS, Cowan JE, Simko J, Roberge G, Stohr BA, Carroll PR, Cooperberg MR. Application of a Prognostic Gleason Grade Grouping System to Assess Distant Prostate Cancer Outcomes. European Urology 2016, 71: 750-759. PMID: 27940155, DOI: 10.1016/j.eururo.2016.11.032.Peer-Reviewed Original ResearchConceptsRisk of PCSMGleason grade groupBone metastasesProstate Strategic Urologic Research Endeavor (CaPSURE) registryGroup ICox proportional hazards modelGrade groupBone metastatic progressionGrade group IPrimary androgen deprivationPrognostic grade groupingKaplan-Meier methodProstate cancer outcomesProportional hazards modelGroup VProstate cancer pathologyNondefinitive therapyDefinitive therapyConservative managementUnadjusted riskAndrogen deprivationGleason sumGleason scoreCancer outcomesGrouping system