2018
334 Whole Exome Sequencing of End Stage Renal Disease Associated Papillary Renal Cell Carcinoma (PRCCs)
Farooq T, Saeed F, Zhang D, Huang W, Yin C, Zhong M. 334 Whole Exome Sequencing of End Stage Renal Disease Associated Papillary Renal Cell Carcinoma (PRCCs). American Journal Of Clinical Pathology 2018, 149: s144-s144. DOI: 10.1093/ajcp/aqx127.333.Peer-Reviewed Original ResearchEnd-stage renal diseasePapillary renal cell carcinomaRenal cell carcinomaSporadic papillary renal cell carcinomasWhole-exome sequencingCell carcinomaExome sequencingSurgical pathology databaseSporadic renal cell carcinomaSpecific genetic alterationsParaffin-embedded tissuesGenomic DNARenal diseasePathology databaseCarcinomaProfile levelsGene mutationsGenetic mutationsGenetic alterationsFrequent mutationsMolecular changesSingle nucleotide variantsTargeted sequencingHuge overlapRNA kit
2016
TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation Cancers
Argani P, Zhong M, Reuter V, Fallon J, Epstein J, Netto G, Antonescu C. TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation Cancers. The American Journal Of Surgical Pathology 2016, 40: 723-737. PMID: 26975036, PMCID: PMC4864095, DOI: 10.1097/pas.0000000000000631.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCarcinoma, Renal CellChildChild, PreschoolChromosomes, Artificial, BacterialChromosomes, Human, XFemaleHumansIn Situ Hybridization, FluorescenceKidney NeoplasmsMaleMelanomaMiddle AgedOncogene Proteins, FusionPerivascular Epithelioid Cell NeoplasmsTranslocation, GeneticYoung AdultConceptsRenal cell carcinomaGene fusionsMelanotic Xp11 translocation renal cancerXp11 translocation renal cell carcinomaTranslocation renal cell carcinomaBacterial artificial chromosome probesGene partnersClinicopathologic featuresClinicopathologic associationsRenal cancerFusion gene partnersClear cell papillary renal cell carcinomaPerivascular epithelioid cell tumorCathepsin KCellular contextPapillary renal cell carcinomaEpithelioid cell tumorRNA sequencingSpecific clinicopathologic featuresMesenchymal counterpartsIdentical gene fusionsOncogenic activationASPL-TFE3 gene fusionChromosome probesTFE3 gene fusions