Benign and Malignant Brenner Tumors Show an Absence of TERT Promoter Mutations That Are Commonly Present in Urothelial Carcinoma
Khani F, Diolombi M, Khattar P, Huang W, Fallon J, Epstein J, Zhong M. Benign and Malignant Brenner Tumors Show an Absence of TERT Promoter Mutations That Are Commonly Present in Urothelial Carcinoma. The American Journal Of Surgical Pathology 2016, 40: 1291-1295. PMID: 27299795, DOI: 10.1097/pas.0000000000000680.Peer-Reviewed Original ResearchConceptsTERT promoter mutationsTransitional cell differentiationMalignant Brenner tumorBrenner tumorUrothelial carcinomaPromoter mutationsMetastatic urothelial carcinomaTransitional cell metaplasiaParaffin-embedded tissue blocksUncommon ovarian neoplasmsPolymerase chain reaction sequencingDistinct pathogenesisCell metaplasiaOvarian neoplasmsPrognostic roleImmunophenotypical featuresFallopian tubeRare caseTransitional epitheliumCell differentiationDiagnostic utilityTumorsTissue blocksReaction sequencingMetaplasia