2016
Benign and Malignant Brenner Tumors Show an Absence of TERT Promoter Mutations That Are Commonly Present in Urothelial Carcinoma
Khani F, Diolombi M, Khattar P, Huang W, Fallon J, Epstein J, Zhong M. Benign and Malignant Brenner Tumors Show an Absence of TERT Promoter Mutations That Are Commonly Present in Urothelial Carcinoma. The American Journal Of Surgical Pathology 2016, 40: 1291-1295. PMID: 27299795, DOI: 10.1097/pas.0000000000000680.Peer-Reviewed Original ResearchConceptsTERT promoter mutationsTransitional cell differentiationMalignant Brenner tumorBrenner tumorUrothelial carcinomaPromoter mutationsMetastatic urothelial carcinomaTransitional cell metaplasiaParaffin-embedded tissue blocksUncommon ovarian neoplasmsPolymerase chain reaction sequencingDistinct pathogenesisCell metaplasiaOvarian neoplasmsPrognostic roleImmunophenotypical featuresFallopian tubeRare caseTransitional epitheliumCell differentiationDiagnostic utilityTumorsTissue blocksReaction sequencingMetaplasiaTFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation Cancers
Argani P, Zhong M, Reuter V, Fallon J, Epstein J, Netto G, Antonescu C. TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation Cancers. The American Journal Of Surgical Pathology 2016, 40: 723-737. PMID: 26975036, PMCID: PMC4864095, DOI: 10.1097/pas.0000000000000631.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCarcinoma, Renal CellChildChild, PreschoolChromosomes, Artificial, BacterialChromosomes, Human, XFemaleHumansIn Situ Hybridization, FluorescenceKidney NeoplasmsMaleMelanomaMiddle AgedOncogene Proteins, FusionPerivascular Epithelioid Cell NeoplasmsTranslocation, GeneticYoung AdultConceptsRenal cell carcinomaGene fusionsMelanotic Xp11 translocation renal cancerXp11 translocation renal cell carcinomaTranslocation renal cell carcinomaBacterial artificial chromosome probesGene partnersClinicopathologic featuresClinicopathologic associationsRenal cancerFusion gene partnersClear cell papillary renal cell carcinomaPerivascular epithelioid cell tumorCathepsin KCellular contextPapillary renal cell carcinomaEpithelioid cell tumorRNA sequencingSpecific clinicopathologic featuresMesenchymal counterpartsIdentical gene fusionsOncogenic activationASPL-TFE3 gene fusionChromosome probesTFE3 gene fusions
2001
Novel tumor-promoting property of tamoxifen.
Zhong M, Lu Z, Abbas T, Hornia A, Chatakondu K, Barile N, Kaplan P, Foster D. Novel tumor-promoting property of tamoxifen. Molecular Cancer Research 2001, 12: 187-92. PMID: 11331247.Peer-Reviewed Original ResearchConceptsTumor-promoting capabilitiesEstrogen antagonist propertiesEstrogen-mimetic effectsEffect of tamoxifenBreast cancer patientsYears of treatmentTumor-promoting phorbol ester TPATumor-promoting propertiesC-Src overexpressionEndometrial cancerCancer patientsRat fibroblastsTamoxifenPhorbol ester TPA