2009
Variation in orbitofrontal cortex volume: relation to sex, emotion regulation and affect
Welborn BL, Papademetris X, Reis DL, Rajeevan N, Bloise SM, Gray JR. Variation in orbitofrontal cortex volume: relation to sex, emotion regulation and affect. Social Cognitive And Affective Neuroscience 2009, 4: 328-339. PMID: 20019072, PMCID: PMC2799952, DOI: 10.1093/scan/nsp028.Peer-Reviewed Original ResearchConceptsAffective individual differencesEmotion regulationIndividual differencesSelf-reported emotion regulation strategiesVmPFC volumeSex differencesEmotion regulation strategiesOrbitofrontal Cortex SubregionsHealthy right-handed adultsVentromedial prefrontal cortexBrain structuresRight-handed adultsEmotion suppressionPositive emotionsBrain volumeRegulation strategiesSomatic anxietyEmotional impulsesOrbitofrontal cortex structurePrefrontal cortexPlanum temporaleLateral orbitofrontalRight lateral orbitofrontalCortex volumeCortex structureFunctional connectivity and alterations in baseline brain state in humans
Martuzzi R, Ramani R, Qiu M, Rajeevan N, Constable RT. Functional connectivity and alterations in baseline brain state in humans. NeuroImage 2009, 49: 823-834. PMID: 19631277, PMCID: PMC2764802, DOI: 10.1016/j.neuroimage.2009.07.028.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnesthesiaAnesthetics, InhalationBrainBrain MappingFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMethyl EthersNerve NetNeural PathwaysPainSevofluraneYoung AdultConceptsDefault mode networkMAC sevoflurane anesthesiaBaseline brain activityFunctional connectivity fMRISevoflurane anesthesiaHigher-order brain regionsAnesthetized conditionSensory cortexDifferent brain networksBaseline activityBrain regionsHuman volunteersSensory areasFunctional connectivityAnesthesiaMode networkLow-level sensory areasBrain networksBrain activityCognitive regionsBrain propertiesBrain statesFurther evidencePainThalamus
1999
Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT.
Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB. Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT. Journal Of Nuclear Medicine 1999, 40: 1902-12. PMID: 10565788.Peer-Reviewed Original ResearchMeSH KeywordsAdultBenzamidesBrainContrast MediaCorpus StriatumFemaleHumansImage Processing, Computer-AssistedIodine RadioisotopesMalePyrrolidinesReceptors, Dopamine D2Regression AnalysisTomography, Emission-Computed, Single-PhotonConceptsSignificant intersubject variabilityD2 receptorsBlood dataDistribution volumeExtrastriatal dopamine D2 receptorsIntersubject variabilityExtrastriatal D2 receptorsDopamine D2 receptorsSingle blood samplingReceptor-containing regionsNondisplaceable compartmentNondisplaceable distribution volumeHealthy volunteersBlood samplingD2 bindingSPECT studiesTissue ratioPlasma samplesPresence of metabolitesMultilinear regression analysisRegression analysisStriatalReceptorsMetabolite activityLipophilic metabolites
1998
Alterations of Benzodiazepine Receptors in Type II Alcoholic Subjects Measured With SPECT and 123IIomazenil
Abi-Dargham A, Krystal JH, Anjilvel S, Scanley BE, Zoghbi S, Baldwin RM, Rajeevan N, Ellis S, Petrakis IL, Seibyl JP, Charney DS, Laruelle M, Innis RB. Alterations of Benzodiazepine Receptors in Type II Alcoholic Subjects Measured With SPECT and 123IIomazenil. American Journal Of Psychiatry 1998, 155: 1550-1555. PMID: 9812116, DOI: 10.1176/ajp.155.11.1550.Peer-Reviewed Original ResearchConceptsHealthy comparison subjectsBenzodiazepine receptorsComparison subjectsAlcoholic subjectsDistribution volumeAlcoholic patientsAnterior cingulateBenzodiazepine receptor densityRight middle frontal gyrusLeft occipital cortexType II alcoholismSingle photon emissionMiddle frontal gyrusStatistical parametric mappingContinuous infusionReceptor radiotracerReceptor densityOccipital cortexCerebellar cortexCortical regionsPatientsFrontal gyrusInterest analysisVivo studiesParametric mappingSignificance of nonuniform attenuation correction in quantitative brain SPECT imaging.
Rajeevan N, Zubal IG, Ramsby SQ, Zoghbi SS, Seibyl J, Innis RB. Significance of nonuniform attenuation correction in quantitative brain SPECT imaging. Journal Of Nuclear Medicine 1998, 39: 1719-26. PMID: 9776276.Peer-Reviewed Original ResearchConceptsHealthy control subjectsHealthy human control subjectsHuman control subjectsControl subjectsDisease patientsGroup of patientsParkinson's disease patientsNonuniform attenuation correctionOutcome measuresParkinson's diseaseSPECT scansBrain SPECTBrain regionsDopamine transporterPatientsBackground activity ratioNonuniform attenuation mapGold standardModerate improvementScansBrain ROIsSPECT imagesAttenuation correctionDiseaseQuantitative brain SPECT