Outcomes of Malignant CNS Ependymomas: An Examination of 2408 Cases Through the Surveillance, Epidemiology, and End Results (SEER) Database (1973–2005)
Rodríguez D, Cheung MC, Housri N, Quinones-Hinojosa A, Camphausen K, Koniaris LG. Outcomes of Malignant CNS Ependymomas: An Examination of 2408 Cases Through the Surveillance, Epidemiology, and End Results (SEER) Database (1973–2005). Journal Of Surgical Research 2009, 156: 340-351. PMID: 19577759, PMCID: PMC7371344, DOI: 10.1016/j.jss.2009.04.024.Peer-Reviewed Original ResearchMeSH KeywordsAdultCentral Nervous System NeoplasmsEpendymomaFemaleHumansMaleSEER ProgramTreatment OutcomeUnited StatesConceptsEnd Results (SEER) databaseSurgical resectionCNS ependymomasMedian survivalResults databaseRadiation therapyMultivariate analysisIntracranial tumor locationOverall median survivalRole of surgeryFive-year survivalSignificant survival benefitLonger median survivalGrade III tumorsPrimary tumor siteLack of radiationMedian agePatient ageSurvival benefitImproved survivalIndependent predictorsAnnual incidenceMalignant ependymomaSurgical extirpationPatient survival