2009
Secondary Lymphoid Organs: Responding to Genetic and Environmental Cues in Ontogeny and the Immune Response
Ruddle NH, Akirav EM. Secondary Lymphoid Organs: Responding to Genetic and Environmental Cues in Ontogeny and the Immune Response. The Journal Of Immunology 2009, 183: 2205-2212. PMID: 19661265, PMCID: PMC2766168, DOI: 10.4049/jimmunol.0804324.Peer-Reviewed Original ResearchConceptsSecondary lymphoid organsLymphoid tissueLymphoid organsImmune responseLymphoid tissue organizer cellsBronchus-associated lymphoid tissueLymphoid tissue inducerTertiary lymphoid tissueSLO developmentLymphoid chemokinesIL-17Lymph nodesLymphoid folliclesPeyer's patchesIL-7Crucial cytokineMucosal tissuesOrganizer cellsCellular accumulationCytokinesTissueOrgansEnvironmental cuesCryptopatchesAdenoids
2006
Lymphoid organ development: from ontogeny to neogenesis
Drayton DL, Liao S, Mounzer RH, Ruddle NH. Lymphoid organ development: from ontogeny to neogenesis. Nature Immunology 2006, 7: 344-353. PMID: 16550197, DOI: 10.1038/ni1330.Peer-Reviewed Original ResearchConceptsBronchial-associated lymphoid tissueTertiary lymphoid organsSecondary lymphoid organsLymphoid organsLymphoid tissueNasal-associated lymphoid tissueSpecific developmentalCellular accumulationLymphoid neogenesisLymph nodesChronic inflammationPeyer's patchesAnatomic locationOntogenyEnvironmental influencesOrgansTissue
1994
10 Studies of Tolerance, Inflammation, and Autoimmunity in Transgenic Mice
Antonia S, Elliott E, Guerder S, Picarella D, Ruddle N, Flavell R. 10 Studies of Tolerance, Inflammation, and Autoimmunity in Transgenic Mice. 1994, 155-174. DOI: 10.1016/b978-0-12-105760-2.50014-5.Peer-Reviewed Original ResearchAutoreactive T cellsT cellsTransgenic miceT antigen transgenic miceLocal antigen presentationSpecific T cellsInfluence of cytokinesAutoreactive cellsAntigen presentationTissue destructionEffective antigenAutoimmunityClonal expansionMiceTissue remodelingStudy of toleranceAntigenIsletsCellsTissueActivationInflammationHyperplasiaCytokinesExpression