1993
The lymphotoxin promoter is stimulated by HTLV-I tax activation of NF-κB in human T-cell lines
Paul N, Millet I, Ruddle N. The lymphotoxin promoter is stimulated by HTLV-I tax activation of NF-κB in human T-cell lines. Cytokine 1993, 5: 372-378. PMID: 7505113, DOI: 10.1016/1043-4666(93)90070-l.Peer-Reviewed Original Research1-Methyl-3-isobutylxanthineBase SequenceBinding SitesCell LineCell NucleusChloramphenicol O-AcetyltransferaseColforsinCyclic AMPCytotoxicity, ImmunologicGene Products, taxHuman T-lymphotropic virus 1HumansLymphotoxin-alphaMolecular Sequence DataNF-kappa BOligodeoxyribonucleotidesPromoter Regions, GeneticRepetitive Sequences, Nucleic AcidT-LymphocytesTransfectionTumor Cells, Cultured
1987
Lymphotoxin: Cloning, Regulation and Mechanism of Killing
Ruddle N, Li C, Tang W, Gray P, McGrath K. Lymphotoxin: Cloning, Regulation and Mechanism of Killing. Novartis Foundation Symposia 1987, 131: 64-87. PMID: 3502460, DOI: 10.1002/9780470513521.ch6.Peer-Reviewed Original ResearchConceptsCDNA libraryBamHI fragmentMurine genomic libraryFull-length cDNACOS-1 cellsCell linesT cell linesNorthern blot analysisGenomic libraryMechanism of killingCDNA probeDNA fragmentationChromosome 17T cell receptorRNABlot analysisCDNAGenesCell receptorCell clonesCellsTarget cellsFragmentsMRNA expressionCloning