1994
Abnormal Development of Peripheral Lymphoid Organs in Mice Deficient in Lymphotoxin
De Togni P, Goellner J, Ruddle N, Streeter P, Fick A, Mariathasan S, Smith S, Carlson R, Shornick L, Strauss-Schoenberger J, Russell J, Karr R, Chaplin D. Abnormal Development of Peripheral Lymphoid Organs in Mice Deficient in Lymphotoxin. Science 1994, 264: 703-707. PMID: 8171322, DOI: 10.1126/science.8171322.Peer-Reviewed Original ResearchConceptsPeripheral lymphoid organsPeripheral bloodLymphoid organsT cellsDetectable lymph nodesT cell subsetsLymph nodesCD4-CD8Cell subsetsPeyer's patchesMice DeficientImmunoglobulin MWhite pulpLymphotoxinLytic functionNormal ratioAbnormal developmentSpleenStem cellsBloodNormal developmentOrgansCellsLymphocytesThymus
1993
The lymphotoxin promoter is stimulated by HTLV-I tax activation of NF-κB in human T-cell lines
Paul N, Millet I, Ruddle N. The lymphotoxin promoter is stimulated by HTLV-I tax activation of NF-κB in human T-cell lines. Cytokine 1993, 5: 372-378. PMID: 7505113, DOI: 10.1016/1043-4666(93)90070-l.Peer-Reviewed Original Research1-Methyl-3-isobutylxanthineBase SequenceBinding SitesCell LineCell NucleusChloramphenicol O-AcetyltransferaseColforsinCyclic AMPCytotoxicity, ImmunologicGene Products, taxHuman T-lymphotropic virus 1HumansLymphotoxin-alphaMolecular Sequence DataNF-kappa BOligodeoxyribonucleotidesPromoter Regions, GeneticRepetitive Sequences, Nucleic AcidT-LymphocytesTransfectionTumor Cells, Cultured